Gene: STK11 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR Morphology-dependent resonances in a large dielectric sphere: An asymptotic calculation using local coordinates. 9908348 1992
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 CausalMutation group CLINVAR Mutation analysis of the STK11/LKB1 gene and clinical characteristics of an Australian series of Peutz-Jeghers syndrome patients. 12372054 2002
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 CausalMutation group CLINVAR Mutations and impaired function of LKB1 in familial and non-familial Peutz-Jeghers syndrome and a sporadic testicular cancer. 9887330 1999
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR Mutations and impaired function of LKB1 in familial and non-familial Peutz-Jeghers syndrome and a sporadic testicular cancer. 9887330 1999
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 CausalMutation group CLINVAR Mutations in the human LKB1/STK11 gene. 16110486 2005
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 CausalMutation group CLINVAR Nine novel germline mutations of STK11 in ten families with Peutz-Jeghers syndrome. 9760200 1998
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 CausalMutation group CLINVAR Novel and recurrent mutations of STK11 gene in six Chinese cases with Peutz-Jeghers syndrome. 24604241 2014
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR Novel mutations in the LKB1/STK11 gene in Dutch Peutz-Jeghers families. 10408777 1999
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR Novel mutations in the STK11 gene in Thai patients with Peutz-Jeghers syndrome. 19908348 2009
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 CausalMutation group CLINVAR Pathogenesis of adenocarcinoma in Peutz-Jeghers syndrome. 9850045 1998
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR Peutz-Jeghers families unlinked to STK11/LKB1 gene mutations are highly predisposed to primitive biliary adenocarcinoma. 11389158 2001
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 CausalMutation group CLINVAR Peutz-Jeghers families unlinked to STK11/LKB1 gene mutations are highly predisposed to primitive biliary adenocarcinoma. 11389158 2001
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group BEFREE Peutz-Jeghers Syndrome (PJS) is a hereditary cancer predisposing syndrome caused by autosomal dominant mutations in the serine/threonine kinase 11 (STK11) gene and is associated with decreased life expectancy. 29720104 2018
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR Predicting the functional effect of amino acid substitutions and indels. 23056405 2012
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR Prevalence of germline PTEN, BMPR1A, SMAD4, STK11, and ENG mutations in patients with moderate-load colorectal polyps. 23399955 2013
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR Relative frequency and morphology of cancers in STK11 mutation carriers. 15188174 2004
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 CausalMutation group CLINVAR Relative frequency and morphology of cancers in STK11 mutation carriers. 15188174 2004
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR SIRT1 modulation of the acetylation status, cytosolic localization, and activity of LKB1. Possible role in AMP-activated protein kinase activation. 18687677 2008
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 CausalMutation group CLINVAR Somatic mutations in the STK11/LKB1 gene are uncommon in rare gynecological tumor types associated with Peutz-Jegher's syndrome. 10623683 2000
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR STK11 domain XI mutations: candidate genetic drivers leading to the development of dysplastic polyps in Peutz-Jeghers syndrome. 24652667 2014
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR STK11 genotyping and cancer risk in Peutz-Jeghers syndrome. 15863673 2005
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 CausalMutation group CLINVAR STK11 genotyping and cancer risk in Peutz-Jeghers syndrome. 15863673 2005
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 CausalMutation group CLINVAR STK11 mutations in Peutz-Jeghers syndrome and sporadic colon cancer. 9809980 1998
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 GeneticVariation group CLINVAR Structure of the LKB1-STRAD-MO25 complex reveals an allosteric mechanism of kinase activation. 19892943 2009
Entrez Id: 6794
Gene Symbol: STK11
STK11 		0.120 CausalMutation group CLINVAR Structure of the LKB1-STRAD-MO25 complex reveals an allosteric mechanism of kinase activation. 19892943 2009