Gene: RAD50 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		0.100 CausalMutation group CLINVAR Almost 2% of Spanish breast cancer families are associated to germline pathogenic mutations in the ATM gene. 27913932 2017
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		0.100 CausalMutation group CLINVAR The frequency of cancer predisposition gene mutations in hereditary breast and ovarian cancer patients in Taiwan: From BRCA1/2 to multi-gene panels. 28961279 2017
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		0.100 CausalMutation group CLINVAR Multigene testing of moderate-risk genes: be mindful of the missense. 26787654 2016
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		0.100 CausalMutation group CLINVAR Multiple gene sequencing for risk assessment in patients with early-onset or familial breast cancer. 26824983 2016
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		0.100 CausalMutation group CLINVAR Hereditary truncating mutations of DNA repair and other genes in BRCA1/BRCA2/PALB2-negatively tested breast cancer patients. 26822949 2016
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		0.100 CausalMutation group CLINVAR Detection of inherited mutations for hereditary cancer using target enrichment and next generation sequencing. 25151137 2015
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		0.100 GeneticVariation group CLINVAR Human RAD50 makes a functional DNA-binding complex. 25828805 2015
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		0.100 CausalMutation group CLINVAR Inherited mutations in 17 breast cancer susceptibility genes among a large triple-negative breast cancer cohort unselected for family history of breast cancer. 25452441 2015
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		0.100 CausalMutation group CLINVAR Use of Whole Genome Sequencing for Diagnosis and Discovery in the Cancer Genetics Clinic. 26023681 2015
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		0.100 GeneticVariation group CLINVAR Detection of novel germline mutations for breast cancer in non-BRCA1/2 families. 26094658 2015
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		0.100 GeneticVariation group CLINVAR Use of Whole Genome Sequencing for Diagnosis and Discovery in the Cancer Genetics Clinic. 26023681 2015
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		0.100 GeneticVariation group CLINVAR Next-generation sequencing for the diagnosis of hereditary breast and ovarian cancer using genomic capture targeting multiple candidate genes. 24549055 2014
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		0.100 CausalMutation group CLINVAR Utilization of multigene panels in hereditary cancer predisposition testing: analysis of more than 2,000 patients. 24763289 2014
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		0.100 CausalMutation group CLINVAR Next-generation sequencing for the diagnosis of hereditary breast and ovarian cancer using genomic capture targeting multiple candidate genes. 24549055 2014
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		0.100 CausalMutation group CLINVAR Germline and somatic mutations in homologous recombination genes predict platinum response and survival in ovarian, fallopian tube, and peritoneal carcinomas. 24240112 2014
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		0.100 GeneticVariation group CLINVAR Rare key functional domain missense substitutions in MRE11A, RAD50, and NBN contribute to breast cancer susceptibility: results from a Breast Cancer Family Registry case-control mutation-screening study. 24894818 2014
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		0.100 CausalMutation group CLINVAR Rare key functional domain missense substitutions in MRE11A, RAD50, and NBN contribute to breast cancer susceptibility: results from a Breast Cancer Family Registry case-control mutation-screening study. 24894818 2014
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		0.100 CausalMutation group CLINVAR Germline variants in MRE11/RAD50/NBN complex genes in childhood leukemia. 24093751 2013
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		0.100 CausalMutation group CLINVAR RAD50 and NBS1 are not likely to be susceptibility genes in Chinese non-BRCA1/2 hereditary breast cancer. 21811815 2012
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		0.100 CausalMutation group CLINVAR ABC ATPase signature helices in Rad50 link nucleotide state to Mre11 interface for DNA repair. 21441914 2011
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		0.100 CausalMutation group CLINVAR Unique DNA repair gene variations and potential associations with the primary antibody deficiency syndromes IgAD and CVID. 20805886 2010
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		0.100 CausalMutation group CLINVAR Mre11-Rad50-Nbs1 conformations and the control of sensing, signaling, and effector responses at DNA double-strand breaks. 21035407 2010
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		0.100 CausalMutation group CLINVAR RAD50 gene mutations are not likely a risk factor for breast cancer in Poland. 20571869 2010
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		0.100 CausalMutation group CLINVAR Some common mutations of RAD50 and NBS1 in western populations do not contribute significantly to Chinese non-BRCA1/2 hereditary breast cancer. 19904603 2010
Entrez Id: 10111
Gene Symbol: RAD50
RAD50 		0.100 CausalMutation group CLINVAR Breast cancer susceptibility: current knowledge and implications for genetic counselling. 19092773 2009