Gene: MSH2 ×
Source: CLINVAR ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 CausalMutation group CLINVAR Risk of colorectal polyps and of malignancies in asymptomatic carriers of mutations in the main DNA mismatch repair genes. 29025352 2018
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 CausalMutation group CLINVAR The spectrum of genetic variants in hereditary pancreatic cancer includes Fanconi anemia genes. 28687971 2018
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 GeneticVariation group CLINVAR In Silico Systems Biology Analysis of Variants of Uncertain Significance in Lynch Syndrome Supports the Prioritization of Functional Molecular Validation. 28765196 2017
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 CausalMutation group CLINVAR Assessment of the InSiGHT Interpretation Criteria for the Clinical Classification of 24 MLH1 and MSH2 Gene Variants. 27629256 2017
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 GeneticVariation group CLINVAR A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America. 28874130 2017
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 GeneticVariation group CLINVAR Assessment of the InSiGHT Interpretation Criteria for the Clinical Classification of 24 MLH1 and MSH2 Gene Variants. 27629256 2017
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 CausalMutation group CLINVAR Upper tract urothelial carcinomas: frequency of association with mismatch repair protein loss and lynch syndrome. 27713421 2017
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 CausalMutation group CLINVAR Elucidating the molecular basis of MSH2-deficient tumors by combined germline and somatic analysis. 28577310 2017
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 CausalMutation group CLINVAR Hereditary cancer syndromes in Latino populations: genetic characterization and surveillance guidelines. 28127413 2017
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 CausalMutation group CLINVAR A survey of the clinicopathological and molecular characteristics of patients with suspected Lynch syndrome in Latin America. 28874130 2017
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 CausalMutation group CLINVAR Targeted sequencing of 36 known or putative colorectal cancer susceptibility genes. 28944238 2017
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 CausalMutation group CLINVAR Spectrum of mismatch repair gene mutations and clinical presentation of Hispanic individuals with Lynch syndrome. 28449805 2017
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 CausalMutation group CLINVAR Detection of Mismatch Repair Deficiency and Microsatellite Instability in Colorectal Adenocarcinoma by Targeted Next-Generation Sequencing. 27863258 2017
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 CausalMutation group CLINVAR Prevalence and Spectrum of Germline Cancer Susceptibility Gene Mutations Among Patients With Early-Onset Colorectal Cancer. 27978560 2017
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 CausalMutation group CLINVAR Correlation between germline mutations in MMR genes and microsatellite instability in ovarian cancer specimens. 28176205 2017
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 CausalMutation group CLINVAR Multigene Panel Testing Provides a New Perspective on Lynch Syndrome. 28514183 2017
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 CausalMutation group CLINVAR Predicting the impact of Lynch syndrome-causing missense mutations from structural calculations. 28422960 2017
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 CausalMutation group CLINVAR Analysis of Lynch Syndrome Mismatch Repair Genes in Women with Endometrial Cancer. 27398995 2016
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 CausalMutation group CLINVAR Oligonucleotide-directed mutagenesis screen to identify pathogenic Lynch syndrome-associated MSH2 DNA mismatch repair gene variants. 26951660 2016
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 CausalMutation group CLINVAR Multilocus Inherited Neoplasia Alleles Syndrome: A Case Series and Review. 26659639 2016
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 GeneticVariation group CLINVAR Lynch syndrome mutation spectrum in New South Wales, Australia, including 55 novel mutations. 27064304 2016
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 CausalMutation group CLINVAR The role of germline mutations in the BRCA1/2 and mismatch repair genes in men ascertained for early-onset and/or familial prostate cancer. 26289772 2016
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 GeneticVariation group CLINVAR DNA Mismatch Repair Deficiency in Rectal Cancer: Benchmarking Its Impact on Prognosis, Neoadjuvant Response Prediction, and Clinical Cancer Genetics. 27432916 2016
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 CausalMutation group CLINVAR Lynch syndrome mutation spectrum in New South Wales, Australia, including 55 novel mutations. 27064304 2016
Entrez Id: 4436
Gene Symbol: MSH2
MSH2 		0.130 CausalMutation group CLINVAR Incidental germline variants in 1000 advanced cancers on a prospective somatic genomic profiling protocol. 26787237 2016