×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.100
CausalMutation
group
CLINVAR
A case of contralateral breast cancer and skin cancer associated with NBN heterozygous pathogenic variant c.698_701delAACA.
28374160
2017
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.100
CausalMutation
group
CLINVAR
Acquired CDK6 amplification promotes breast cancer resistance to CDK4/6 inhibitors and loss of ER signaling and dependence.
27748766
2017
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.100
CausalMutation
group
CLINVAR
Genetic Predisposition to Breast Cancer Due to Mutations Other Than BRCA1 and BRCA2 Founder Alleles Among Ashkenazi Jewish Women.
28727877
2017
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.100
CausalMutation
group
CLINVAR
Exome sequencing covers >98% of mutations identified on targeted next generation sequencing panels.
28152038
2017
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.100
CausalMutation
group
CLINVAR
Gene panel sequencing in familial breast/ovarian cancer patients identifies multiple novel mutations also in genes others than BRCA1/2.
27616075
2017
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.100
CausalMutation
group
CLINVAR
Hereditary truncating mutations of DNA repair and other genes in BRCA1/BRCA2/PALB2-negatively tested breast cancer patients.
26822949
2016
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.100
CausalMutation
group
CLINVAR
Frequency of Germline Mutations in 25 Cancer Susceptibility Genes in a Sequential Series of Patients With Breast Cancer.
26976419
2016
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.100
CausalMutation
group
CLINVAR
Panel Testing for Familial Breast Cancer: Calibrating the Tension Between Research and Clinical Care.
26786923
2016
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.100
CausalMutation
group
CLINVAR
Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing.
26681312
2016
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.100
CausalMutation
group
CLINVAR
Multigene testing of moderate-risk genes: be mindful of the missense.
26787654
2016
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.100
CausalMutation
group
CLINVAR
The c.657del5 variant in the NBN gene predisposes to pancreatic cancer.
27150568
2016
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.100
CausalMutation
group
CLINVAR
Heterozygous germline mutations in NBS1 among Korean patients with high-risk breast cancer negative for BRCA1/2 mutation.
25712764
2015
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.100
CausalMutation
group
CLINVAR
Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer.
26315354
2015
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.100
CausalMutation
group
CLINVAR
Nijmegen breakage syndrome detected by newborn screening for T cell receptor excision circles (TRECs).
25677497
2015
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.100
CausalMutation
group
CLINVAR
Prevalence of Germline Mutations in Genes Engaged in DNA Damage Repair by Homologous Recombination in Patients with Triple-Negative and Hereditary Non-Triple-Negative Breast Cancers.
26083025
2015
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.100
GeneticVariation
group
CLINVAR
Germline Mutations in the BRIP1, BARD1, PALB2, and NBN Genes in Women With Ovarian Cancer.
26315354
2015
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.100
CausalMutation
group
CLINVAR
Frequency of mutations in individuals with breast cancer referred for BRCA1 and BRCA2 testing using next-generation sequencing with a 25-gene panel.
25186627
2015
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.100
CausalMutation
group
CLINVAR
Identification of a Variety of Mutations in Cancer Predisposition Genes in Patients With Suspected Lynch Syndrome.
25980754
2015
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.100
CausalMutation
group
CLINVAR
Rare key functional domain missense substitutions in MRE11A, RAD50, and NBN contribute to breast cancer susceptibility: results from a Breast Cancer Family Registry case-control mutation-screening study.
24894818
2014
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.100
CausalMutation
group
CLINVAR
Identification of the interactors of human nibrin (NBN) and of its 26 kDa and 70 kDa fragments arising from the NBN 657del5 founder mutation.
25485873
2014
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.100
CausalMutation
group
CLINVAR
Utilization of multigene panels in hereditary cancer predisposition testing: analysis of more than 2,000 patients.
24763289
2014
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.100
CausalMutation
group
CLINVAR
Next-generation sequencing for the diagnosis of hereditary breast and ovarian cancer using genomic capture targeting multiple candidate genes.
24549055
2014
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.100
CausalMutation
group
CLINVAR
Significant association between Nijmegen breakage syndrome 1 657del5 polymorphism and breast cancer risk.
23765759
2013
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.100
CausalMutation
group
CLINVAR
An inherited NBN mutation is associated with poor prognosis prostate cancer.
23149842
2013
×
Entrez Id:
4683
Gene Symbol:
NBN
NBN
0.100
CausalMutation
group
CLINVAR
Functional variants in NBS1 and cancer risk: evidence from a meta-analysis of 60 publications with 111 individual studies.
24113799
2013