Gene: POLE ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5426
Gene Symbol: POLE
POLE 		0.100 CausalMutation group CLINVAR Frequency and phenotypic spectrum of germline mutations in POLE and seven other polymerase genes in 266 patients with colorectal adenomas and carcinomas. 25529843 2015
Entrez Id: 5426
Gene Symbol: POLE
POLE 		0.100 CausalMutation group CLINVAR Germline variants in POLE are associated with early onset mismatch repair deficient colorectal cancer. 25370038 2015
Entrez Id: 5426
Gene Symbol: POLE
POLE 		0.100 CausalMutation group CLINVAR New insights into POLE and POLD1 germline mutations in familial colorectal cancer and polyposis. 24501277 2014
Entrez Id: 5426
Gene Symbol: POLE
POLE 		0.100 CausalMutation group CLINVAR Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas. 23263490 2013
Entrez Id: 5426
Gene Symbol: POLE
POLE 		0.100 CausalMutation group CLINVAR A method to select for mutator DNA polymerase deltas in Saccharomyces cerevisiae. 16699561 2006
Entrez Id: 5426
Gene Symbol: POLE
POLE 		0.100 CausalMutation group CLINVAR Crystal structures of an NH2-terminal fragment of T4 DNA polymerase and its complexes with single-stranded DNA and with divalent metal ions. 8679562 1996