Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Genotype-specific progression of hereditary medullary thyroid cancer. 29656518 2018
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 GeneticVariation group BEFREE Activating RET mutations found in the inherited cancer syndrome multiple endocrine neoplasia 2 permit early diagnosis, predict disease course and guide disease management to optimize patient survival. 29743166 2018
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 Biomarker group BEFREE MEN2A is a hereditary cancer-predisposing syndrome that affects patients with germline RET mutations. 29197744 2018
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Different RET gene mutation-induced multiple endocrine neoplasia type 2A in 3 Chinese families. 28099363 2017
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Distribution of RET Mutations in Multiple Endocrine Neoplasia 2 in Denmark 1994-2014: A Nationwide Study. 27809725 2017
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Genotype-Phenotype Correlation in Patients With Germline Mutations of VHL, RET, SDHB, and SDHD Genes: Thai Experience. 28469506 2017
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR How to Assess the Clinical Relevance of Novel RET Missense Variants in the Absence of Functional Studies? 27099842 2016
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Germline mutations and genotype-phenotype correlation in Asian Indian patients with pheochromocytoma and paraganglioma. 27539324 2016
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Medullary Thyroid Carcinoma Associated with Germline RETK666N Mutation. 27673361 2016
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Disease-modifying polymorphisms and C609Y mutation of RET associated with high penetrance of phaeochromocytoma and low rate of MTC in MEN2A. 27994876 2016
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Screening for germline mutations in breast/ovarian cancer susceptibility genes in high-risk families in Israel. 26687385 2016
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Actionable exomic incidental findings in 6503 participants: challenges of variant classification. 25637381 2015
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Molecular diagnosis and comprehensive treatment of multiple endocrine neoplasia type 2 in Southeastern Chinese. 25628771 2015
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Skewed mutational spectrum of RET proto-oncogene Exon10 in Iranian patients with medullary thyroid carcinoma. 25694125 2015
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Revised American Thyroid Association guidelines for the management of medullary thyroid carcinoma. 25810047 2015
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR RET Cys634Arg mutation confers a more aggressive multiple endocrine neoplasia type 2A phenotype than Cys634Tyr mutation. 25515555 2015
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR A NOVEL DOUBLE MUTATION VAL648ILE AND VAL804LEU OF RET PROTO-ONCOGENE IN MULTIPLE ENDOCRINE NEOPLASIA TYPE 2. 26247112 2015
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Recommendations for somatic and germline genetic testing of single pheochromocytoma and paraganglioma based on findings from a series of 329 patients. 26269449 2015
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Characterization of V804M-mutated RET proto-oncogene associated with familial medullary thyroid cancer, report of the largest Turkish family. 25501606 2015
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR RET revisited: expanding the oncogenic portfolio. 24561444 2014
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR A newly identified missense mutation in RET codon 666 is associated with the development of medullary thyroid carcinoma. 25319874 2014
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Patient affected by neurofibromatosis type 1 and thyroid C-cell hyperplasia harboring pathogenic germ-line mutations in both NF1 and RET genes. 24361808 2014
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR The rare intracellular RET mutation p.S891A in a Chinese Han family with familial medullary thyroid carcinoma. 24845513 2014
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR In silico profiling and structural insights of missense mutations in RET protein kinase domain by molecular dynamics and docking approach. 24336963 2014
Entrez Id: 5979
Gene Symbol: RET
RET 		0.200 CausalMutation group CLINVAR Multiple endocrine neoplasia type 2A in an Iranian family: clinical and genetic studies. 24784869 2014