| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | AlteredExpression | disease | BEFREE | The levels of urinary MCP-1 increased in parallel to the enhancement of total urine protein in 24 h in HSPN patients. | 28919104 | 2018 | ||||
|
0.070 | Biomarker | disease | BEFREE | However, injection of exosomes from BSA-treated CCL2-deficient TECs induced less severe kidney inflammation. | 29295871 | 2018 | ||||
|
0.070 | Biomarker | disease | BEFREE | 54 SLE patients without nephritis, 35 with nephritis but without dialysis, and 4 with nephritis under dialysis exhibited stepwise increases in IL-23 (<i>p</i>=0.009) and MCP-1 (<i>p</i>=0.015). | 27814627 | 2017 | ||||
|
0.070 | AlteredExpression | disease | LHGDN | TNF-alpha can play a crucial role in the immunopathogenesis of nephritis by the induction of CCL2, ICAM-1 and VCAM-1 expression via the activation of the intracellular MAPK signaling pathway, which may contribute to macrophage and lymphocyte infiltration. | 18656701 | 2008 | ||||
|
0.070 | Biomarker | disease | BEFREE | SLE patients had higher MCP-1 concentrations than controls (p < 0.0001), African American patients had higher concentrations than Caucasian patients (p = 0.006), and patients with nephritis had higher concentrations than those without nephritis (p = 0.02). | 17407231 | 2007 | ||||
|
0.070 | Biomarker | disease | BEFREE | An NH2-terminal deletion mutant of the MCP-1 gene (7ND) was injected into the skeletal muscles of MRL/Ipr mice with advanced stage nephritis to suppress MCP-1 and its receptor (CCR2) signaling pathway. | 15895897 | 2005 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | These results suggest that a genetic polymorphism in the 5' flanking region of the MCP-1 gene would be associated with nephritis in lupus through modulating MCP-1 expression. | 12460032 | 2002 | ||||
|
0.070 | AlteredExpression | disease | LHGDN | These results suggest that a genetic polymorphism in the 5' flanking region of the MCP-1 gene would be associated with nephritis in lupus through modulating MCP-1 expression. | 12460032 | 2002 |