Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3913
Gene Symbol: LAMB2
LAMB2
0.220 Biomarker disease MGD
Entrez Id: 6357
Gene Symbol: CCL13
CCL13
0.010 AlteredExpression disease LHGDN CCL13 and HSPC159 mRNA expressions in PBMC from MCNS patients in nephrosis were significantly higher than those in nephrotic MN patients and healthy controls. 18219197 2008
Entrez Id: 10439
Gene Symbol: OLFM1
OLFM1
0.010 Biomarker disease BEFREE Olfm-1 and myocilin are markedly induced in podocytes during PAN nephrosis and appear to be involved in the processes that govern the reorganization of the actin cytoskeleton during podocyte repair. 20595200 2011
Entrez Id: 7225
Gene Symbol: TRPC6
TRPC6
0.010 Biomarker disease BEFREE Trpc6 inactivation confers protection in a model of severe nephrosis in rats. 29785489 2018
Entrez Id: 1636
Gene Symbol: ACE
ACE
0.200 Biomarker disease RGD Angiotensin I converting enzyme activity in adriamycin induced nephrosis in rats. 8303709 1993
Entrez Id: 10630
Gene Symbol: PDPN
PDPN
0.200 Biomarker disease RGD Podoplanin, novel 43-kd membrane protein of glomerular epithelial cells, is down-regulated in puromycin nephrosis. 9327748 1997
Entrez Id: 3913
Gene Symbol: LAMB2
LAMB2
0.220 Biomarker disease LHGDN A syndrome comprising childhood-onset glomerular kidney disease and ocular abnormalities with progressive loss of vision is caused by mutated LAMB2. 16921188 2006
Entrez Id: 1909
Gene Symbol: EDNRA
EDNRA
0.010 Biomarker disease BEFREE Antiproteinuric effect of an endothelin-1 receptor antagonist in puromycin aminonucleoside-induced nephrosis in rat. 29360807 2018
Entrez Id: 29094
Gene Symbol: LGALSL
LGALSL
0.010 AlteredExpression disease LHGDN CCL13 and HSPC159 mRNA expressions in PBMC from MCNS patients in nephrosis were significantly higher than those in nephrotic MN patients and healthy controls. 18219197 2008
Entrez Id: 29094
Gene Symbol: LGALSL
LGALSL
0.010 AlteredExpression disease BEFREE CCL13 and HSPC159 mRNA expressions in PBMC from MCNS patients in nephrosis were significantly higher than those in nephrotic MN patients and healthy controls. 18219197 2008
Entrez Id: 284
Gene Symbol: ANGPT1
ANGPT1
0.200 Biomarker disease RGD Changes in angiopoietin expression in glomeruli involved in glomerulosclerosis in rats with daunorubicin-induced nephrosis. 16626513 2006
Entrez Id: 966
Gene Symbol: CD59
CD59
0.200 Biomarker disease RGD Complement inhibitors targeted to the proximal tubule prevent injury in experimental nephrotic syndrome and demonstrate a key role for C5b-9. 15843577 2005
Entrez Id: 4868
Gene Symbol: NPHS1
NPHS1
0.020 Biomarker disease BEFREE Congenital nephrotic syndrome of the Finnish type (NPHS1) is an autosomal-recessive disorder, characterized by massive proteinuria in utero and nephrosis at birth. 9660941 1998
Entrez Id: 64816
Gene Symbol: CYP3A43
CYP3A43
0.200 Biomarker disease CTD_rat Contribution of down-regulation of intestinal and hepatic cytochrome P450 3A to increased absorption of cyclosporine A in a rat nephrosis model. 18725544 2008
Entrez Id: 1577
Gene Symbol: CYP3A5
CYP3A5
0.200 Biomarker disease CTD_rat Contribution of down-regulation of intestinal and hepatic cytochrome P450 3A to increased absorption of cyclosporine A in a rat nephrosis model. 18725544 2008
Entrez Id: 64816
Gene Symbol: CYP3A43
CYP3A43
0.200 Biomarker disease RGD Contribution of down-regulation of intestinal and hepatic cytochrome P450 3A to increased absorption of cyclosporine A in a rat nephrosis model. 18725544 2008
Entrez Id: 1577
Gene Symbol: CYP3A5
CYP3A5
0.200 Biomarker disease RGD Contribution of down-regulation of intestinal and hepatic cytochrome P450 3A to increased absorption of cyclosporine A in a rat nephrosis model. 18725544 2008
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.010 AlteredExpression disease BEFREE Downregulation of vascular endothelial growth factor and its receptors in the kidney in rats with puromycin aminonucleoside nephrosis. 11744811 2002
Entrez Id: 10076
Gene Symbol: PTPRU
PTPRU
0.200 Biomarker disease RGD Early changes in gene expression that influence the course of primary glomerular disease. 17457373 2007
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
0.500 Biomarker disease RGD Effect of a specific endothelin receptor A antagonist and an angiotensin-converting enzyme inhibitor on glomerular mRNA levels for extracellular matrix components, metalloproteinases (MMP) and a tissue inhibitor of MMP in aminonucleoside nephrosis. 9175058 1997
Entrez Id: 26762
Gene Symbol: HAVCR1
HAVCR1
0.210 Biomarker disease RGD Effect of combining ACE inhibition with aldosterone blockade on proteinuria and renal damage in experimental nephrosis. 17213874 2007
Entrez Id: 335
Gene Symbol: APOA1
APOA1
0.020 Biomarker disease BEFREE Effect of experimental nephrosis on hepatic lipoprotein secretion and urinary lipoprotein excretion in rats expressing the human apolipoprotein A-I gene. 8725162 1996
Entrez Id: 1649
Gene Symbol: DDIT3
DDIT3
0.500 Biomarker disease RGD Expression and function of C/EBP homology protein (GADD153) in podocytes. 16400006 2006
Entrez Id: 1649
Gene Symbol: DDIT3
DDIT3
0.500 Biomarker disease CTD_human Expression and function of C/EBP homology protein (GADD153) in podocytes. 16400006 2006
Entrez Id: 1524
Gene Symbol: CX3CR1
CX3CR1
0.200 Biomarker disease RGD Expression of the chemokine fractalkine (FKN/CX3CL1) by podocytes in normal and proteinuric rat kidney glomerulus. 19590241 2009