Gene: APP ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Inhibition of human high-affinity copper importer Ctr1 orthologous in the nervous system of Drosophila ameliorates Aβ42-induced Alzheimer's disease-like symptoms. 23827522 2013
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Time course study of Aβ formation and neurite outgrowth disruption in differentiated human neuroblastoma cells exposed to H2O2: protective role of autophagy. 23726866 2013
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Early effects of aluminum chloride on beta-secretase mRNA expression in a neuronal model of beta-amyloid toxicity. 20111991 2010
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Anti-amyloidogenic effect of AA3E2 attenuates beta-amyloid induced toxicity in SK-N-MC cells. 20359466 2010
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Alzheimer's-associated Abeta oligomers show altered structure, immunoreactivity and synaptotoxicity with low doses of oleocanthal. 19631677 2009
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human A novel compound, maltolyl p-coumarate, attenuates cognitive deficits and shows neuroprotective effects in vitro and in vivo dementia models. 17600377 2007
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Estrogenic agonist activity of ICI 182,780 (Faslodex) in hippocampal neurons: implications for basic science understanding of estrogen signaling and development of estrogen modulators with a dual therapeutic profile. 16951259 2006
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Overexpression of superoxide dismutase 1 protects against beta-amyloid peptide toxicity: effect of estrogen and copper chelators. 12963085 2004
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human EGb 761 is a neuroprotective agent against beta-amyloid toxicity. 12396081 2002
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Methotrexate-related nonnecrotizing multifocal axonopathy detected by beta-amyloid precursor protein immunohistochemistry. 11800653 2002
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker phenotype CTD_human Contrasting, species-dependent modulation of copper-mediated neurotoxicity by the Alzheimer's disease amyloid precursor protein. 11784781 2002