Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
0.430 Biomarker phenotype CTD_human Lack of synergistic effect of resveratrol and sigma-1 receptor agonist (PRE-084) in SOD1G⁹³A ALS mice: overlapping effects or limited therapeutic opportunity? 24885036 2014
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
0.430 Biomarker phenotype LHGDN Cu/Zn superoxide dismutase typical for familial amyotrophic lateral sclerosis increases the vulnerability of mitochondria and perturbs Ca2+ homeostasis in SOD1G93A mice. 19060114 2009
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
0.430 Biomarker phenotype CTD_human Peroxymonocarbonate and carbonate radical displace the hydroxyl-like oxidant in the Sod1 peroxidase activity under physiological conditions. 19243126 2009
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
0.430 GeneticVariation phenotype LHGDN These results suggest that the misfolding of ALS-related mutant SOD1 induces ER stress possibly prior to the formation of visible aggregates, which may contribute to the motor neuron degeneration in ALS pathogenesis. 18233996 2008
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
0.430 Biomarker phenotype CTD_human SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis. 17581637 2007
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
0.430 Biomarker phenotype LHGDN Magnetic resonance imaging reveals neuronal degeneration in the brainstem of the superoxide dismutase 1 transgenic mouse model of amyotrophic lateral sclerosis. 15379995 2004
Entrez Id: 6647
Gene Symbol: SOD1
SOD1
0.430 Biomarker phenotype HPO