Gene: DVL2 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1856
Gene Symbol: DVL2
DVL2 		0.030 GeneticVariation group BEFREE Recently, we have reported a possible role for rare variants of DVL2 as risk factors for NTDs. 23836490 2013
Entrez Id: 1856
Gene Symbol: DVL2
DVL2 		0.030 Biomarker group BEFREE In this study, we analyzed the role of the human orthologs DVL2 and DVL3 in a cohort of 473 patients with neural tube defects. 22892949 2013
Entrez Id: 1856
Gene Symbol: DVL2
DVL2 		0.030 GeneticVariation group BEFREE Our biochemical analyses revealed that among the five mutations, N356K and R45W show loss-of-function or reduced activities in inducing Dishevelled2 (DVL2) degradation and inhibiting jun-N-terminal kinase (JNK) phosphorylation, implicating mutated DACT1 as a risk factor for human NTDs. 22610794 2012