Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2055
Gene Symbol: CLN8
CLN8
0.400 GeneticVariation disease BEFREE The NCLs include eight forms that result from genetic deficiency on genes CLN(1) to CLN(8), respectively: four classic forms with clinical onset at varying ages-infantile (INCL), late-infantile (LINCL), juvenile (JNCL), and adult (ANCL)-and four variants of late-infantile onset-the Finnish variant LINCL (fLINCL), Portuguese variant LINCL (pLINCL), Turkish variant LINCL (tLINCL), and progressive epilepsy with mental retardation (EPMR). 11001811 2000
Entrez Id: 2055
Gene Symbol: CLN8
CLN8
0.400 Biomarker disease BEFREE A homozygous mutation in the orthologous mouse gene (Cln8) underlies the phenotype of a naturally occurring NCL model, the motor neuron degeneration mouse (mnd). 10861296 2000
Entrez Id: 2055
Gene Symbol: CLN8
CLN8
0.400 CausalMutation disease CLINVAR The neuronal ceroid lipofuscinosis CLN8 membrane protein is a resident of the endoplasmic reticulum. 10861296 2000
Entrez Id: 2055
Gene Symbol: CLN8
CLN8
0.400 Biomarker disease BEFREE The murine orthologue of CLN8 causes motor neuron degeneration (mnd), a mouse model of NCL. 11073223 2000
Entrez Id: 2055
Gene Symbol: CLN8
CLN8
0.400 Biomarker disease BEFREE Neuropathological findings have shown that EPMR is a new member (CLN8) of the neuronal ceroid lipofuscinosis (NCL) group of neurodegenerative disorders.The CLN8 gene was identified recently. 11073227 2000
Entrez Id: 2055
Gene Symbol: CLN8
CLN8
0.400 GeneticVariation disease BEFREE It displays 82% nucleotide identity with CLN8, conservation of the codon harbouring the human mutation and is localized to the same region as the motor neuron degeneration mouse, mnd, a naturally occurring mouse NCL (ref.4). 10508524 1999
Entrez Id: 2055
Gene Symbol: CLN8
CLN8
0.400 Biomarker disease MGD An early-onset congenic strain of the motor neuron degeneration (mnd) mouse. 10191135 1999
Entrez Id: 2055
Gene Symbol: CLN8
CLN8
0.400 Biomarker disease MGD Retinal degeneration in motor neuron degeneration (mnd) mutant mice. 8282051 1993
Entrez Id: 2055
Gene Symbol: CLN8
CLN8
0.400 Biomarker disease MGD Motor neuron degeneration of mice is a model of neuronal ceroid lipofuscinosis (Batten's disease). 7683855 1993
Entrez Id: 2055
Gene Symbol: CLN8
CLN8
0.400 Biomarker disease MGD Mapping of the motor neuron degeneration (Mnd) gene, a mouse model of amyotrophic lateral sclerosis (ALS). 1639406 1992
Entrez Id: 2055
Gene Symbol: CLN8
CLN8
0.400 Biomarker disease MGD Autosomal dominance in a late-onset motor neuron disease in the mouse. 3783318 1986
Entrez Id: 2055
Gene Symbol: CLN8
CLN8
0.400 GeneticVariation disease CLINVAR