Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.400 Biomarker disease BEFREE Recent studies demonstrate that brain-derived neurotrophic factor (BDNF) might be associated with nicotine addiction, and circulating BDNF is a biomarker of memory and general cognitive function. 30659208 2019
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.400 AlteredExpression disease BEFREE BDNF levels did not correlate with severity of nicotine dependence, age of the cases or duration of opioid dependence. 29859931 2018
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.400 GeneticVariation disease BEFREE Some recent studies show an association between a functional polymorphism of BDNF gene (Val66Met) and the susceptibility to nicotine dependence and we hypothesized that this polymorphism was associated with smoking in both schizophrenia patients and healthy controls. 25455509 2015
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.400 Biomarker disease BEFREE Nicotine dependence and number of cigarettes smoked per day did not add to the prediction of serum BDNF; however, total number of smoking years was a significant predictor of serum BDNF. 25183693 2015
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.400 GeneticVariation disease BEFREE In patients with a current diagnosis of depression or anxiety, the relationship between nicotine dependence and symptom severity may be moderated by BDNF Val(66)Met. 25618300 2015
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.400 Biomarker disease BEFREE In application to a real dataset, we detected one significant tetragenic interaction among CHRNA4, CHRNB2, BDNF, and NTRK2 associated with nicotine dependence in the Study of Addiction: Genetics and Environment sample, suggesting the biological role of these genes in nicotine dependence development. 24057800 2014
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.400 Biomarker disease BEFREE Association studies have also suggested that the BDNF gene might play a role in the susceptibility to nicotine dependence but results appear contradictory. 23285275 2012
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.400 Biomarker disease BEFREE Emerging evidence indicates that the DRD1-BDNF-DRD3 cluster plays an important role in nicotine addiction. 20456319 2010
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.400 Biomarker disease BEFREE By using a generalized multifactor dimensionality reduction algorithm recently developed by us, we found highly significant gene-gene interactions for the gene pairs of CHRNA4 and CHRNB2, CHRNA4 and NTRK2, CHRNB2 and NTRK2, and BDNF and NTRK2 (p < .01 for all four gene pairs) and significant gene-gene interaction between CHRNA4 and BDNF (p = .031) on ND. 18534558 2008
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.400 Biomarker disease CTD_human Association of the met66 allele of brain-derived neurotrophic factor (BDNF) with smoking. 17186223 2007
Entrez Id: 627
Gene Symbol: BDNF
BDNF
0.400 GeneticVariation disease BEFREE The significant association of BDNF variants with ND implies that this gene plays a role in the etiology of ND in EAs and that its involvement is gender specific. 16152573 2005