Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.580 | Biomarker | disease | BEFREE | Cytochrome P450 2E1 (CYP2E1) can be induced by diabetes mellitus, nonalcoholic liver disease, and obesity. | 30991910 | 2019 | ||||
|
0.580 | AlteredExpression | disease | BEFREE | CYP2E1 activity and children with obesity: possible confounding factors. | 30334271 | 2019 | ||||
|
0.580 | Biomarker | disease | BEFREE | Our study is consistent with previous research and further claimes that CNVs containing CYP2E1 may be related to HTG and obesity. | 29129660 | 2018 | ||||
|
0.580 | AlteredExpression | disease | BEFREE | The enhanced levels of CYP2E1 and increased oxidative stress in obesity play a significant role in this process. | 25180626 | 2014 | ||||
|
0.580 | Biomarker | disease | BEFREE | The protein encoded by CYP2E1 involves the synthesis of cholesterol, steroids and other lipids, which may have a potential impact on obesity. | 23175694 | 2013 | ||||
|
0.580 | Biomarker | disease | BEFREE | We investigated a possible association between alcoholism, cigarette smoking, obesity and CYP2E1 RsaI and 96-bp insertion genetic polymorphisms with risk for colorectal cancer (CRC). | 23007992 | 2012 | ||||
|
0.580 | Biomarker | disease | BEFREE | These trends are consistent with the characteristic phenotype of obesity in the transgenic rat because CYP4A1 and CYP2E1 enhance fatty acid excretion and glyconeogenesis from fatty acids respectively. | 10647907 | 1999 | ||||
|
0.580 | Biomarker | disease | BEFREE | A genetic polymorphism in the regulatory sequences of human CYP2E1: association with increased chlorzoxazone hydroxylation in the presence of obesity and ethanol intake. | 9772223 | 1998 |