| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | Biomarker | disease | BEFREE | Epigenomics and metabolomics reveal the mechanism of the APOA2-saturated fat intake interaction affecting obesity. | 29901700 | 2018 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Several investigations have been conducted regarding the interaction between Apolipoprotein A2 (APOA2) -265 T>C polymorphism and dietary intake of saturated fatty acids (SFAs) on obesity in healthy individuals or type 2 diabetes mellitus (T2 DM) patients. | 28359369 | 2017 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | The objective of this study was to analyze the interaction of a high fat diet with the APOA2 (rs3813627 and rs5082), APOA5 (rs662799 and rs3135506) and LEPR (rs8179183 and rs1137101) polymorphisms and its relationship with obesity and dyslipidemia in young subjects. | 26365669 | 2015 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | We also re-analyse cross-sectional data from the Framingham study on a gene-diet interaction between an APOA2 polymorphism and high saturated fat intake on obesity. | 23558781 | 2013 | ||||
|
0.080 | Biomarker | disease | BEFREE | In this study, we evaluated relationships between APOA2 and obesity risk with particular focus on patterns of eating and ghrelin, a hormonal regulator of food intake. | 21386805 | 2012 | ||||
|
0.080 | Biomarker | disease | BEFREE | We have reported an APOA2-saturated fat interaction determining body mass index (BMI) and obesity in American populations. | 20975728 | 2011 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | We analyzed gene-diet interactions between the APOA2 -265T>C polymorphism and saturated fat intake on BMI and obesity in 3462 individuals from 3 populations in the United States: the Framingham Offspring Study (1454 whites), the Genetics of Lipid Lowering Drugs and Diet Network Study (1078 whites), and Boston-Puerto Rican Centers on Population Health and Health Disparities Study (930 Hispanics of Caribbean origin). | 19901143 | 2009 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | The -265T>C polymorphism is consistently associated with food consumption and obesity, suggesting a new role for APOA2 in regulating dietary intake. | 17446329 | 2007 |