Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 114798
Gene Symbol: SLITRK1
SLITRK1
0.050 GeneticVariation disease BEFREE Gene variations in PBX1, LMX1A and SLITRK1 are associated with obsessive-compulsive disorder and its clinical features. 30377043 2019
Entrez Id: 114798
Gene Symbol: SLITRK1
SLITRK1
0.050 GeneticVariation disease BEFREE These important functional differences in the N400I variant, as compared to the wildtype SLITRK1 sequence, may contribute to OCD and OC spectrum symptoms. 23990902 2013
Entrez Id: 114798
Gene Symbol: SLITRK1
SLITRK1
0.050 GeneticVariation disease BEFREE Rare genetic variants of SLITRK1 have been previously associated with Tourette syndrome (TS), attention-deficit/hyperactivity disorder (ADHD), and obsessive-compulsive disorder (OCD) symptoms. 19640509 2009
Entrez Id: 114798
Gene Symbol: SLITRK1
SLITRK1
0.050 Biomarker disease BEFREE As several other uncommon, less well quantitated genetic variations occur with an OCD phenotype, including chromosomal anomalies and some other rare gene variants (SGCE, GCH1 and SLITRK1), a tentative conclusion is that OCD resembles other complex disorders in being etiologically heterogeneous and in having both highly penetrant familial subtypes associated with rare alleles or chromosomal anomalies, as well as having a more common, polygenetic form that may involve polymorphisms in such genes as BDNF, COMT, GRIN2beta, TPH2, HTR2A and SLC1A1. 18197083 2008
Entrez Id: 114798
Gene Symbol: SLITRK1
SLITRK1
0.050 Biomarker disease BEFREE Psychopathological features of obsessive-compulsive disorder in an Italian family with Gilles de la Tourette syndrome not linked to the SLITRK1 gene. 18722020 2008