Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | GeneticVariation | disease | BEFREE | We investigated the association of DRD4 VNTR polymorphism with OCD and its relationship with various clinical parameters (age of onset, gender, family history, co-morbidity, factor-analyzed symptom dimensions and insight). | 23127570 | 2013 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | In our study we observed transmission disequilibrium for the 48-bp repeat polymorphism of the DRD4 gene using the ETDT (P=0.047) in 69 trios comprising patients with early onset OCD and both of their parents. | 18446263 | 2008 | ||||
|
0.080 | Biomarker | disease | BEFREE | In conclusion, the current study cannot exclude an association between DRD4 gene and OCD in the largest sample analyzed. | 16996722 | 2007 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | The genetic studies yielded statistically significant results when the allelic distributions of genetic variants in the dopamine receptor type 4 gene (DRD4) were analysed in the Caucasian OCD cohort. | 15488960 | 2004 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | This study is the first to report on a significant association of variants of the DRD4 gene in OCD, found on both family- and population-based studies. | 12497615 | 2003 | ||||
|
0.080 | Biomarker | disease | BEFREE | The distribution of selected polymorphic variants in the serotonin receptor type 2A and 1Dbeta (5-HT(2A), 5-HT(1Dbeta)), dopamine transporter (DAT), dopamine receptor type 4 (DRD4) and monoamine-oxidase A (MAO-A) genes were analysed in 71 OCD cases and 129 control individuals in the genetically homogeneous Afrikaner population, by means of case-control association studies. | 12650952 | 2003 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Our study suggests that the seven-repeat allele of the DRD4 gene could be a factor in the phenotypic variance of tics among OCD individuals. | 9280153 | 1997 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Association study of a null mutation in the dopamine D4 receptor gene in Italian patients with obsessive-compulsive disorder, bipolar mood disorder and schizophrenia. | 8902887 | 1996 |