Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 26050
Gene Symbol: SLITRK5
SLITRK5
0.320 Biomarker disease BEFREE Treatment of OCD-like grooming behavior in Slitrk5, SAPAP3, and laser-stimulated mice with one dose of RG108 (DNA methyltransferase inhibitor), lead to marked symptom improvement lasting for at least one week as well as complete reversal of anomalous changes in circuitry and PP1 gene methylation. 31217515 2019
Entrez Id: 26050
Gene Symbol: SLITRK5
SLITRK5
0.320 GeneticVariation disease BEFREE These results demonstrate that rare functional mutations in SLITRK5 contribute to the genetic risk for OCD in human populations. 28085938 2017
Entrez Id: 26050
Gene Symbol: SLITRK5
SLITRK5
0.320 Biomarker disease CTD_human Thus, our studies identify Slitrk5 as an essential molecule at corticostriatal synapses and provide a new mouse model of OCD-like behaviors. 20418887 2010