Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4128
Gene Symbol: MAOA
MAOA
0.090 GeneticVariation disease BEFREE Transmission disequilibrium analyses were performed after genotyping 13 single-nucleotide polymorphisms (eight in COMT and five in MAO-A) in 783 OCD trios (probands and their parents). 25793616 2015
Entrez Id: 4128
Gene Symbol: MAOA
MAOA
0.090 GeneticVariation disease BEFREE Association study between MAO-A gene promoter VNTR polymorphisms and obsessive-compulsive disorder. 23746491 2013
Entrez Id: 4128
Gene Symbol: MAOA
MAOA
0.090 GeneticVariation disease BEFREE In the main meta-analysis, OCD was associated with serotonin-related polymorphisms (5-HTTLPR and HTR2A) and, in males only, with polymorphisms involved in catecholamine modulation (COMT and MAOA). 22665263 2013
Entrez Id: 4128
Gene Symbol: MAOA
MAOA
0.090 GeneticVariation disease BEFREE Females with OCD (1) reported more sexual abuse during childhood than males, (2) often noted changes in obsessive-compulsive symptoms in the premenstrual/menstrual period as well as during/shortly after pregnancy, and with menopause, and (3) in the Caucasian subgroup, were more frequently homozygous for the low activity C allele of the EcoRV variant of the MAO-A gene compared to controls, with this allele also more frequent in female patients than controls. 15013025 2004
Entrez Id: 4128
Gene Symbol: MAOA
MAOA
0.090 GeneticVariation disease BEFREE Females with OCD (1) reported more sexual abuse during childhood than males, (2) often noted changes in obsessive-compulsive symptoms in the premenstrual/menstrual period as well as during/shortly after pregnancy, and with menopause, and (3) in the Caucasian subgroup, were more frequently homozygous for the low activity C allele of the EcoRV variant of the MAO-A gene compared to controls, with this allele also more frequent in female patients than controls. 15468463 2004
Entrez Id: 4128
Gene Symbol: MAOA
MAOA
0.090 GeneticVariation disease BEFREE There are several reported associations between depressive disorders, panic disorder, and obsessive-compulsive disorder (OCD) and a variety of polymorphisms in the monoamine oxidase A (MAOA) gene. 12815746 2003
Entrez Id: 4128
Gene Symbol: MAOA
MAOA
0.090 Biomarker disease BEFREE The distribution of selected polymorphic variants in the serotonin receptor type 2A and 1Dbeta (5-HT(2A), 5-HT(1Dbeta)), dopamine transporter (DAT), dopamine receptor type 4 (DRD4) and monoamine-oxidase A (MAO-A) genes were analysed in 71 OCD cases and 129 control individuals in the genetically homogeneous Afrikaner population, by means of case-control association studies. 12650952 2003
Entrez Id: 4128
Gene Symbol: MAOA
MAOA
0.090 GeneticVariation disease BEFREE Haplotype-based haplotype relative risk (HHRR) analysis of the inheritance of the MAO-A variants revealed in the female probands that 14 out of 19 transmitted the allele 1, providing significant evidence for an allelic association between OCD and MAO-A gene. 11353450 2001
Entrez Id: 4128
Gene Symbol: MAOA
MAOA
0.090 GeneticVariation disease BEFREE We also provide evidence for a similar sexually dimorphic association between OCD and an allele of the MAOA gene, previously linked to high MAO-A enzymatic activity. 10331110 1999