| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | Biomarker | group | BEFREE | Biallelic PTCH1 Inactivation Is a Dominant Genomic Change in Sporadic Keratocystic Odontogenic Tumors. | 31725470 | 2020 | ||||
|
0.080 | GeneticVariation | group | BEFREE | Stromal cells were isolated from the fibrous capsules of patients with NBCCS-associated or non-syndromic keratocystic odontogenic tumors and non-syndromic tumor stromal cells without PTCH1 mutations served as controls. | 26890308 | 2016 | ||||
|
0.080 | GeneticVariation | group | BEFREE | PTCH1 gene mutations in Keratocystic odontogenic tumors: a study of 43 Chinese patients and a systematic review. | 24204797 | 2013 | ||||
|
0.080 | GeneticVariation | group | BEFREE | Alterations in the Sonic Hedgehog signaling pathway, including PTCH gene mutations, have been associated with the pathogenesis of some odontogenic tumors. | 22221699 | 2012 | ||||
|
0.080 | GeneticVariation | group | BEFREE | Novel PTCH1 mutations in patients with keratocystic odontogenic tumors screened for nevoid basal cell carcinoma (NBCC) syndrome. | 22952776 | 2012 | ||||
|
0.080 | GeneticVariation | group | BEFREE | A review of the biological behavior of this recognized aggressive pathological entity of the jaws and a contemporary outline of the molecular (growth factors, p53, PCNA and Ki-67, bcl-2) and genetic (PTCH, SHH) alterations associated with this odontogenic neoplasm provides a better understanding of the mechanisms involved in its development and strengthen the current concept that the KCOT should, indeed, be regarded as a neoplasm. | 20004133 | 2010 | ||||
|
0.080 | GeneticVariation | group | BEFREE | Identification of known and novel PTCH mutations in both syndromic and non-syndromic keratocystic odontogenic tumors. | 20690502 | 2009 | ||||
|
0.080 | GeneticVariation | group | LHGDN | PTCH1 and SMO gene alterations in keratocystic odontogenic tumors. | 18502968 | 2008 | ||||
|
0.080 | GeneticVariation | group | BEFREE | PTCH1 and SMO gene alterations in keratocystic odontogenic tumors. | 18502968 | 2008 |