Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 10215
Gene Symbol: OLIG2
OLIG2
0.100 AlteredExpression disease BEFREE FoxG1 indices were similar in astrocytic and oligodendroglial tumours, whereas Olig-2 indices were increased in oligodendrogliomas compared to astrocytic tumours (n = 451, P < 0.0001). 29053887 2018
Entrez Id: 10215
Gene Symbol: OLIG2
OLIG2
0.100 Biomarker disease BEFREE Olig2 was positive in 5 out of 44 ependymomas (11%) and 50 out of 54 (93%) non-ependymal tumors (astrocytomas and oligodendrogliomas). 26287936 2016
Entrez Id: 10215
Gene Symbol: OLIG2
OLIG2
0.100 Biomarker disease BEFREE The means of Olig2 LI in glioma cells were 43.7 % in diffuse astrocytomas, 59.3 % in oligoastrocytomas and 76.1 % in oligodendrogliomas. 25085214 2014
Entrez Id: 10215
Gene Symbol: OLIG2
OLIG2
0.100 Biomarker disease BEFREE The oligodendroglioma areas showed immunoreactivity for Olig2 and mutant isocitrate dehydrogenase 1 protein, whereas the gangliocytoma and neurocytoma areas were positive for synaptophysin and NeuN. 24054724 2013
Entrez Id: 10215
Gene Symbol: OLIG2
OLIG2
0.100 Biomarker disease BEFREE Olig-2 stained 22 (91.6%) of 24 oligodendrogliomas and all dysembryoplastic neuroepithelial tumors but also 24 (80%) of 30 glioblastoma multiforme and 8 (80%) of 10 pilocytic astrocytomas. 21835431 2012
Entrez Id: 10215
Gene Symbol: OLIG2
OLIG2
0.100 Biomarker disease BEFREE A quantitative study showed that the Olig2-positive nuclei were much fewer in ependymomas than in astrocytomas and oligodendrogliomas. 18552083 2008
Entrez Id: 10215
Gene Symbol: OLIG2
OLIG2
0.100 AlteredExpression disease LHGDN In the current study, we found that overexpression of OLIG2 was not only found in oligodendroglioma samples and normal neural tissue but also in a wide spectrum of malignant cell lines including leukemia, non-small cell lung carcinoma, melanoma, and breast cancer cell lines. 16103065 2005
Entrez Id: 10215
Gene Symbol: OLIG2
OLIG2
0.100 AlteredExpression disease BEFREE In the current study, we found that overexpression of OLIG2 was not only found in oligodendroglioma samples and normal neural tissue but also in a wide spectrum of malignant cell lines including leukemia, non-small cell lung carcinoma, melanoma, and breast cancer cell lines. 16103065 2005
Entrez Id: 10215
Gene Symbol: OLIG2
OLIG2
0.100 Biomarker disease BEFREE Recently, two bHLH transcription factors involved in oligodendroglial specification, Olig1 and Olig2 have been proposed as potential markers of oligodendrogliomas. 15164981 2004
Entrez Id: 10215
Gene Symbol: OLIG2
OLIG2
0.100 Biomarker disease LHGDN High OLIG expression alone has been proposed to distinguish oligodendrogliomas from astrocytomas, so we critically evaluated OLIG2 as a marker by immunohistochemical and oligonucleotide microarray analysis. 15198128 2004
Entrez Id: 10215
Gene Symbol: OLIG2
OLIG2
0.100 Biomarker disease BEFREE The oligodendrocyte lineage genes OLIG1 and OLIG2 have been reported as potential diagnostic markers for oligodendrogliomas [Lu et al. 14730454 2004
Entrez Id: 10215
Gene Symbol: OLIG2
OLIG2
0.100 AlteredExpression disease BEFREE In situ hybridization showed that the OLIG2 gene was expressed by tumor cells in pilocytic astrocytomas as well as those in oligodendrogliomas. 12924709 2003
Entrez Id: 10215
Gene Symbol: OLIG2
OLIG2
0.100 AlteredExpression disease BEFREE In conclusion, combining Olig mRNA expression and immunohistochemistry of OLIG2 enables oligodendrogliomas to be distinguished from glioblastomas and other astrocytic glial tumors. 14575240 2003
Entrez Id: 10215
Gene Symbol: OLIG2
OLIG2
0.100 Biomarker disease BEFREE OLIG2-positive cells corresponding to neoplastic oligodendrocytes were present in all oligodendrogliomas and oligoastrocytomas. 11498220 2001