| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.080 | GeneticVariation | disease | BEFREE | Our screening approach could not identify an increased prevalence of HFE gene mutations and iron overload in younger patients with severe osteoarthritis of the hip. | 30427934 | 2018 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | HFE gene mutation carriers were more prevalent among patients with OA than among healthy controls. | 24401005 | 2014 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | HFE C282Y homozygosity was associated with an increased risk of both single and bilateral total hip replacement for osteoarthritis. | 22209421 | 2012 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | Accordingly, it was predicted that the concentration of ferritin in synovial fluid (SF) would be higher in OA patients with HFE gene mutations than in HFE wild-type (wt) OA patients. | 20560808 | 2010 | ||||
|
0.080 | GeneticVariation | disease | LHGDN | The HFE H63D variant may explain, at least in part, the prevalence of arthralgia in multiple joints sites, chondrocalcinosis, and hand osteoarthritis in the general population. | 17284543 | 2007 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | HFE gene mutations are associated with osteoarthritis in the index or middle finger metacarpophalangeal joints. | 16583477 | 2006 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | HFE gene mutations may be a marker for the type 2 polyarticular OA phenotype and a clue to OA pathogenesis. | 16755236 | 2006 | ||||
|
0.080 | GeneticVariation | disease | LHGDN | This is the first report to show an increased risk of OA among individuals who are heterozygous for the C282Y HFE mutation. | 12508400 | 2003 | ||||
|
0.080 | GeneticVariation | disease | BEFREE | This is the first report to show an increased risk of OA among individuals who are heterozygous for the C282Y HFE mutation. | 12508400 | 2003 |