Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3 		0.440 Biomarker disease HPO
Entrez Id: 1311
Gene Symbol: COMP
COMP 		0.440 Biomarker disease HPO
Entrez Id: 8200
Gene Symbol: GDF5
GDF5 		0.420 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 8200
Gene Symbol: GDF5
GDF5 		0.420 Biomarker disease HPO
Entrez Id: 1758
Gene Symbol: DMP1
DMP1 		0.300 Biomarker disease GENOMICS_ENGLAND
Entrez Id: 2487
Gene Symbol: FRZB
FRZB 		0.140 Biomarker disease HPO
Entrez Id: 1280
Gene Symbol: COL2A1
COL2A1 		0.130 Biomarker disease HPO
Entrez Id: 176
Gene Symbol: ACAN
ACAN 		0.110 Biomarker disease HPO
Entrez Id: 6399
Gene Symbol: TRAPPC2
TRAPPC2 		0.100 Biomarker disease HPO
Entrez Id: 59341
Gene Symbol: TRPV4
TRPV4 		0.100 Biomarker disease HPO
Entrez Id: 3106
Gene Symbol: HLA-B
HLA-B 		0.100 Biomarker disease HPO
Entrez Id: 1186
Gene Symbol: CLCN7
CLCN7 		0.100 Biomarker disease HPO
Entrez Id: 3552
Gene Symbol: IL1A
IL1A 		0.030 GeneticVariation disease BEFREE Hip osteoarthritis susceptibility is associated with IL1B -511(G>A) and IL1 RN (VNTR) genotypic polymorphisms in Croatian Caucasian population. 21671260 2011
Entrez Id: 54829
Gene Symbol: ASPN
ASPN 		0.050 GeneticVariation disease BEFREE Hip osteoarthritis is associated with a genetic polymorphism in the aspartic acid repeat in the N-terminal region of the asporin (<i>ASPN</i>) gene; therefore, the present study aimed to investigate whether the CNV of <i>ASPN</i> is involved in the pathogenesis of AD. 28747338 2017
Entrez Id: 1297
Gene Symbol: COL9A1
COL9A1 		0.020 GeneticVariation disease BEFREE COL9A1 may therefore be a susceptibility locus for female hip OA. 10788539 2000
Entrez Id: 6422
Gene Symbol: SFRP1
SFRP1 		0.010 GeneticVariation disease BEFREE Frizzled-related protein variants are risk factors for hip osteoarthritis. 16572458 2006
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		0.010 GeneticVariation disease BEFREE Estrogen receptor alpha genotype is associated with a reduced prevalence of radiographic hip osteoarthritis in elderly Caucasian women. 17419075 2007
Entrez Id: 2099
Gene Symbol: ESR1
ESR1 		0.010 GeneticVariation disease LHGDN Estrogen receptor alpha genotype is associated with a reduced prevalence of radiographic hip osteoarthritis in elderly Caucasian women. 17419075 2007
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		0.150 Biomarker disease BEFREE Transforming growth factor β1 (TGF-β1) and interleukin-6 (IL-6) are two pro-inflammatory cytokines included in pathogenesis of OA, bone remodeling and development of bone and joint tissues. 21353594 2011
Entrez Id: 7291
Gene Symbol: TWIST1
TWIST1 		0.010 AlteredExpression disease BEFREE TWIST1 mRNA expression was elevated and correlated with SMAD3 mRNA levels in the OA cohort during the time-course. 22820497 2012
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		0.150 Biomarker disease BEFREE Transforming growth factor-β1 (TGF-beta1) and interleukin-6 (IL-6) are included in pathogenesis of OA, as well as in development of the musculoskeletal system. 25603974 2015
Entrez Id: 50515
Gene Symbol: CHST11
CHST11 		0.010 AlteredExpression disease BEFREE CHST11 was found to be upregulated in OA versus non-OA cartilage (p < 0.001) and was expressed dynamically during chondrogenesis. 27391021 2016
Entrez Id: 56729
Gene Symbol: RETN
RETN 		0.010 Biomarker disease BEFREE Resistin promotes the abnormal Type I collagen phenotype of subchondral bone in obese patients with end stage hip osteoarthritis. 28642544 2017
Entrez Id: 81793
Gene Symbol: TLR10
TLR10 		0.020 GeneticVariation disease BEFREE TLR10 SNP rs11096957 was found significantly associated with predisposition to hip OA (p = 0.04, OR = 1.41, 95%CI = 1.02-1.94) but not knee OA. 29194748 2018
Entrez Id: 3569
Gene Symbol: IL6
IL6 		0.060 Biomarker disease BEFREE IL6, MDC and IP10 are associated with hip OA pain and these proteins may be able to provide additional information regarding pain in hip OA patients. 29402254 2018