Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 199
Gene Symbol: AIF1
AIF1 		0.010 AlteredExpression disease BEFREE These results suggest that a single injection of duloxetine suppressed mechanical hyperalgesia and may influence the expression of Iba1 in the microglia of the ipsilateral dorsal horn in the MIA-induced hip OA. 31538672 2020
Entrez Id: 2907
Gene Symbol: GRINA
GRINA 		0.010 AlteredExpression disease BEFREE GRINA and PLEC also demonstrated differential expression between OA hip and non-OA hip cartilage. 30730609 2019
Entrez Id: 55660
Gene Symbol: PRPF40A
PRPF40A 		0.010 GeneticVariation disease BEFREE Ten individuals at high risk of developing hip osteoarthritis (SibKids) underwent contemporaneous T2 mapping and dGEMRIC in the hip (10 hips). 30971110 2019
Entrez Id: 112744
Gene Symbol: IL17F
IL17F 		0.010 GeneticVariation disease BEFREE The haplotype G-T (IL17A-IL17F; rs2275913-rs763780) is associated with protection to the disease in hip OA (p < 0.01). 31042000 2019
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.010 Biomarker disease BEFREE Overall our findings provide direct evidence about the importance of β-catenin in hip OA pathogenesis. 30912140 2019
Entrez Id: 410
Gene Symbol: ARSA
ARSA 		0.010 GeneticVariation disease BEFREE One hundred and eighty patients (ASA class I or II) with bilateral hip osteoarthritis were assigned randomly to two equal groups. 29756496 2019
Entrez Id: 2335
Gene Symbol: FN1
FN1 		0.010 AlteredExpression disease BEFREE A significant difference was found in levels of the fibronectin-aggrecan complex (FAC) in patients with OA compared with controls (0.08 ± 0.40 vs 1.15 ± 0.35 μg/mL, respectively; <i>P</i> < .001). 30388026 2019
Entrez Id: 7412
Gene Symbol: VCAM1
VCAM1 		0.010 Biomarker disease BEFREE The results of this study show that serum concentrations of VCAM-1 cannot distinguish patients with severe hip OA from age and sex-matched controls. 31037360 2019
Entrez Id: 49
Gene Symbol: ACR
ACR 		0.010 Biomarker disease BEFREE Data of patients participating in the longitudinal CONTROL-PRO study (patients fulfilling clinical ACR criteria for knee or hip OA) were used. 30299244 2019
Entrez Id: 4615
Gene Symbol: MYD88
MYD88 		0.010 AlteredExpression disease BEFREE The levels of TLRs, MyD88, RANKL, and inflammatory factors in the revision THA (rTHA) with MoM group were higher than those in the hOA group. 29940143 2018
Entrez Id: 57542
Gene Symbol: KLHL42
KLHL42 		0.010 GeneticVariation disease BEFREE Colocalization analysis indicated sharing of genetic signals for hip shape and hip OA for the KLHDC5/PTHLH and COL11A1 loci. 29882636 2018
Entrez Id: 2591
Gene Symbol: GALNT3
GALNT3 		0.010 AlteredExpression disease BEFREE Pain, physical function and activity within the hip OA cohort were examined using the HOOS, SF-36, HHS and UCLA outcome measures. 29402254 2018
Entrez Id: 8600
Gene Symbol: TNFSF11
TNFSF11 		0.010 Biomarker disease BEFREE The levels of TLRs, MyD88, RANKL, and inflammatory factors in the revision THA (rTHA) with MoM group were higher than those in the hOA group. 29940143 2018
Entrez Id: 4792
Gene Symbol: NFKBIA
NFKBIA 		0.010 Biomarker disease BEFREE TLR10 and NFKBIA contributed to the risk of hip osteoarthritis: systematic evaluation based on Han Chinese population. 29980729 2018
Entrez Id: 4185
Gene Symbol: ADAM11
ADAM11 		0.010 Biomarker disease BEFREE IL6, MDC and IP10 are associated with hip OA pain and these proteins may be able to provide additional information regarding pain in hip OA patients. 29402254 2018
Entrez Id: 147495
Gene Symbol: APCDD1
APCDD1 		0.010 AlteredExpression disease BEFREE Pain, physical function and activity within the hip OA cohort were examined using the HOOS, SF-36, HHS and UCLA outcome measures. 29402254 2018
Entrez Id: 6367
Gene Symbol: CCL22
CCL22 		0.010 Biomarker disease BEFREE IL6, MDC and IP10 are associated with hip OA pain and these proteins may be able to provide additional information regarding pain in hip OA patients. 29402254 2018
Entrez Id: 2247
Gene Symbol: FGF2
FGF2 		0.010 AlteredExpression disease BEFREE EGF, FGF2, MCP3, MIP1α, and IL8 were differentially expressed between hip and knee OA cohorts; while FGF2, GRO, IL8, MCP1, and VEGF were differentially expressed between hip OA and control cohorts. 29402254 2018
Entrez Id: 637
Gene Symbol: BID
BID 		0.010 Biomarker disease BEFREE Improvement in WOMAC pain, physical function and stiffness subscales from treatment with SR paracetamol BID versus placebo in subjects with knee or hip OA was not significant. 29239664 2018
Entrez Id: 2717
Gene Symbol: GLA
GLA 		0.010 Biomarker disease BEFREE Good Life with osteoArthritis in Denmark (GLA:D) was launched in 2013 with the aim of implementing guidelines for the treatment of knee and hip OA in clinical care nationwide. 28173795 2017
Entrez Id: 467
Gene Symbol: ATF3
ATF3 		0.010 AlteredExpression disease BEFREE Early elevation of CGRP expression and late expression of ATF-3 were demonstrated in DRG neurons, possibly reflecting inflammatory pain and neuropathic pain in hip OA.© 2017 Orthopaedic Research Society. 27543839 2017
Entrez Id: 780896
Gene Symbol: ACTD
ACTD 		0.010 Biomarker disease BEFREE Cam Deformity and Acetabular Dysplasia as Risk Factors for Hip Osteoarthritis. 27696746 2017
Entrez Id: 56729
Gene Symbol: RETN
RETN 		0.010 Biomarker disease BEFREE Resistin promotes the abnormal Type I collagen phenotype of subchondral bone in obese patients with end stage hip osteoarthritis. 28642544 2017
Entrez Id: 960
Gene Symbol: CD44
CD44 		0.010 Biomarker disease BEFREE Mobilization of the CD44/CD105 positive synovial cells seems to play a role in the genesis of HO. 27803113 2017
Entrez Id: 50964
Gene Symbol: SOST
SOST 		0.010 Biomarker disease BEFREE The current study describes the regional cellular distribution of SOST and DKK-1 in hip OA. 28275825 2017