Gene: SMAD3 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3 		0.440 GeneticVariation disease GWASCAT Identification of new therapeutic targets for osteoarthritis through genome-wide analyses of UK Biobank data. 30664745 2019
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3 		0.440 GeneticVariation disease BEFREE Conclusions The SMAD3 SNP rs12901499 GA genotype and G variant may increase the risk of hip OA in Chinese Han patients. 29310478 2018
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3 		0.440 Biomarker disease CTD_human Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis. 30374069 2018
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3 		0.440 GeneticVariation disease GWASCAT Meta-analysis of Icelandic and UK data sets identifies missense variants in SMO, IL11, COL11A1 and 13 more new loci associated with osteoarthritis. 30374069 2018
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3 		0.440 GeneticVariation disease BEFREE And the pooled results revealed significant association between SMAD3 rs12901499 polymorphism and both knee and hip OA (knee OA: OR 1.18, 95% CI 1.04-1.34; hip OA: OR 1.31, 95% CI 1.18-1.44). 30208919 2018
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3 		0.440 AlteredExpression disease BEFREE Associations were observed between tissue non-specific alkaline phosphatase (TNAP), osteocalcin (OCN), TWIST1, TGFβ1, SMAD3 mRNA levels and mineral measures in OA against CTL. 22820497 2012
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3 		0.440 GeneticVariation disease BEFREE A SNP (rs12901499) mapping to intron 1 of SMAD3 was associated with both knee and hip OA (P < 0.0022 and P < 0.021, respectively) in the discovery set. 20506137 2010
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3 		0.440 Biomarker disease HPO