Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4041
Gene Symbol: LRP5
LRP5
0.020 Biomarker disease BEFREE These pre-clinical studies indicate combination therapies that target LRP5 and TGFβ signaling should increase trabecular bone mass in patients with OI more than targeting either signaling pathway alone. 31648079 2020
Entrez Id: 4041
Gene Symbol: LRP5
LRP5
0.020 Biomarker disease BEFREE Biologic agents that can increase LRP5 and LRP6-mediated WNT signaling could benefit individuals with MESD-associated OI. 31564437 2019