Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.440 Biomarker disease BEFREE To determine whether circulating levels of two matrix metalloproteinases, MMP-2 and MMP-9, are associated with loss of alveolar bone density (ABD) or height (ABH), or with progression of periodontitis (relative clinical attachment level [RCAL]), among postmenopausal women with local and systemic bone loss. 31032961 2019
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.440 Biomarker disease BEFREE However, by using MMP2 short hairpin RNA, we demonstrate that the αvβ6 effect on bone loss is due to upregulation of soluble MMP2 by the cancer cells, not due to changes in tumor growth rate. 24385215 2014
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.440 Biomarker disease CTD_human Recessive inactivating mutations in human matrix metalloproteinase 2 (MMP2, gelatinase A) are associated with syndromes that include abnormal facial appearance, short stature, and severe bone loss. 17440987 2007
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.440 Biomarker disease BEFREE The apparent lack of a murine model [Itoh, T., Ikeda, T., Gomi, H., Nakao, S., Suzuki, T. and Itohara, S. (1997) Unaltered secretion of beta-amyloid precursor protein in gelatinase A (matrix metalloproteinase 2)-deficient mice.J. Biol.Chem., 272, 22389-22392.] has hindered studies on disease pathogenesis and, more fundamentally, in addressing the paradox of how functional loss of a single proteolytic enzyme results in an apparent increase in bone loss. 17400654 2007
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.440 GeneticVariation disease BEFREE Recessive inactivating mutations in human matrix metalloproteinase 2 (MMP2, gelatinase A) are associated with syndromes that include abnormal facial appearance, short stature, and severe bone loss. 17440987 2007
Entrez Id: 4313
Gene Symbol: MMP2
MMP2
0.440 Biomarker disease HPO