The inhibition of MicroRNA-139-5p promoted osteoporosis of bone marrow-derived mesenchymal stem cell by targeting Wnt/beta-catenin signaling pathway by NOTCH1.
Therefore, this research was the first to reveal the critical role of the lncRNA ODSM/miR-139-3p/ELK1 pathway in osteoblasts, and these findings suggest the potential value of miR-139-3p in osteoporosis diagnosis and therapy.