| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | Biomarker | disease | BEFREE | In conclusion, the present data demonstrated that adiponectin has a significant inhibitory effect on the osteoclast differentiation and proliferation of BMMs, suggesting a novel strategy for preventing osteoporosis. | 30679996 | 2019 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | Compared with plaque-free group, patients in the group with calcified plaques were older with a lower BMD, more cases of hypertension, diabetes and hyperlipidemia, higher levels of osteoprotegerin and leptin in serum and lower levels of serum adiponectin and 25 (OH) D. Severe loss of bone mass, osteoporosis and decreased serum level of 25 (OH) D were correlated with the occurrence of calcified plaques in the arteries after confounding factors such as age were adjusted. | 29696936 | 2019 | ||||
|
0.070 | Biomarker | disease | BEFREE | The aim of this research was to assess leptin, adiponectin and resistin secretion in obese postmenopausal women with osteoporosis and determine whether obesity might be a factor mitigating the risk of osteoporosis. | 31566247 | 2019 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | The levels of adipokines, adiponectin and visfatin, in patients without complicating osteoporosis were significantly lower than those in patients complicated with osteoporosis. | 28975973 | 2017 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | We herein focus on the cross-regulation of fat and bone and propose that marrow fat accumulation and reduced serum leptin and adiponectin levels may play important roles in the pathophysiologic process of osteoporosis in patients with lipodystrophy. | 28448764 | 2017 | ||||
|
0.070 | Biomarker | disease | BEFREE | Using the same model, a negative association was seen between adiponectin and BMD at the FN in women with osteoporosis (p = 0.043). | 28646476 | 2017 | ||||
|
0.070 | AlteredExpression | disease | BEFREE | In OA bone, significantly higher expression of PPARγ2 and adiponectin as well as RUNX2, osterix and osteocalcin were obtained, suggesting higher adipogenesis and osteoblastogenesis in OA than in OP. | 21854818 | 2011 |