Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.380 | Biomarker | disease | BEFREE | Dual-luciferase reporter assay demonstrated that Bmi-1 was a direct target gene of miR-330-3p, and in a recovery experiment, miR-330-3p suppressed osteosarcoma cell proliferation by directly targeting Bmi-1. | 29614499 | 2018 | ||||
|
0.380 | AlteredExpression | disease | BEFREE | In addition, overexpression of circRNA-0008717 in osteosarcoma could elevate Bmi-1 expression, resulting in the promotion of osteosarcoma cell proliferation and invasion. | 29854278 | 2018 | ||||
|
0.380 | Biomarker | disease | BEFREE | Bmi-1 and TRIM-14 are associated with the initiation and progression of osteosarcoma, which could promote angiogenesis, invasion, and apoptotic resistance in bone cancer tissue. | 28631557 | 2017 | ||||
|
0.380 | Biomarker | disease | BEFREE | Furthermore, Bmi‑1 promoted osteosarcoma tumor growth, whereas AbBmi‑1 significantly inhibited osteosarcoma tumor growth in vitro and in vivo. | 28983587 | 2017 | ||||
|
0.380 | Biomarker | disease | BEFREE | LncRNA ZFAS1 promotes growth and metastasis by regulating BMI1 and ZEB2 in osteosarcoma. | 28744396 | 2017 | ||||
|
0.380 | Biomarker | disease | BEFREE | The present study aimed to investigate the combinational effects of the small interfering RNAs (siRNAs) c-myc and Bmi-1 on the growth and chemosensitivity of MG-63 osteosarcoma cells. | 23685757 | 2013 | ||||
|
0.380 | Biomarker | disease | BEFREE | These findings suggest a crucial role for BMI-1 in osteosarcoma pathogenesis. | 21311599 | 2011 | ||||
|
0.380 | Biomarker | disease | CTD_human | These findings suggest a crucial role for BMI-1 in osteosarcoma pathogenesis. | 21311599 | 2011 | ||||
|
0.380 | AlteredExpression | disease | BEFREE | Conversely, Bmi1 expression reduced PHC3 at the mRNA level and induced the proliferation of osteosarcoma cells. | 20491773 | 2010 |