Gene: ERBB2 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.400 Biomarker disease BEFREE Phenethyl isothiocyanate hampers growth and progression of HER2-positive breast and ovarian carcinoma by targeting their stem cell compartment. 31376137 2019
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.400 Biomarker disease BEFREE HER2-targeting properties and biodistribution were evaluated in BALB/C <i>nu/nu</i> mice bearing ovarian carcinoma cell (SKOV-3) xenografts. 28864631 2018
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.400 Biomarker disease BEFREE Our results demonstrated that Gigantoxin-4-4D5 scFv exerted a highly cytotoxic effect on the HER2/neu-positive ovarian carcinoma SK-OV-3 cell line. 27063011 2016
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.400 Biomarker disease BEFREE A novel far-red fluorescent xenograft model of ovarian carcinoma for preclinical evaluation of HER2-targeted immunotoxins. 26436696 2015
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.400 Biomarker disease BEFREE In the present study, we explored whether T-DM1 could effectively treat HER2-positive human ovarian carcinoma in vitro and in vivo. 24987913 2014
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.400 AlteredExpression disease BEFREE Polymorphism and overexpression of HER2/neu among ovarian carcinoma women from Tiruchirapalli, Tamil Nadu, India. 23722284 2013
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.400 AlteredExpression disease BEFREE Effect of HER-2/neu overexpression on chemoresistance and prognosis in ovarian carcinoma. 17212661 2007
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.400 Biomarker disease BEFREE HER-2/neu and bcl-2 in ovarian carcinoma: clinicopathologic, immunohistochemical, and molecular study in patients with shorter and longer survival. 16785787 2006
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.400 GeneticVariation disease BEFREE Gene amplification, mutation, and protein expression of EGFR and mutations of ERBB2 in serous ovarian carcinoma. 16607561 2006
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.400 GeneticVariation disease BEFREE Archival tissues from 23 cases of papillary serous ovarian carcinoma (9 cases of stage I and 14 cases of stage III) were analyzed by FISH using a HER-2/neu probe and a chromosome 17 centromere control probe. 10409445 1999
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.400 AlteredExpression disease BEFREE To examine the hypothesis that coamplified and/or coregulated topoisomerase IIalpha contributes to the resistance of c-erbB-2-overexpressing carcinomas, we established a chemosensitivity assay using primary cells from an ovarian carcinoma that overexpressed both c-erbB-2 and topoisomerase IIalpha. 10397267 1999
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.400 Biomarker disease BEFREE HER-2/neu is a proto-oncogene associated with poor prognosis in women with breast and ovarian carcinoma. 10202671 1999
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.400 Biomarker disease BEFREE Furthermore, intraperitoneal delivery of the anti-erbB-2 sFv enhances survival and reduces tumor burden in a xenograft model of human ovarian carcinoma in SCID mice. 9062138 1997
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.400 AlteredExpression disease BEFREE Therefore, neither c-erbB2 gene amplification nor c-erbB2 protein over-expression appears to be a significant prognostic marker in patients with ovarian carcinoma. 7615357 1995
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.400 Biomarker disease BEFREE The amplification rate of C-myc, C-N-ras, C-Ki-ras and C-erbB-2 in ovarian carcinoma were 50%, 44%, 31% and 25% respectively. 8585978 1995
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.400 Biomarker disease BEFREE Activation of c-erbB-2 and prognosis in ovarian carcinoma. Comparison with histologic type, grade, and stage. 7906608 1994
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.400 AlteredExpression disease BEFREE We have previously found that the ovarian carcinoma cell line SK-OV-3 overexpresses c-erbB-2/neu mRNA. 8094034 1993
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.400 Biomarker disease BEFREE The results suggest that amplification of the c-erb B-2/neu gene may play a role in the pathogenesis of ovarian carcinoma. 2569708 1989
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.400 GenomicAlterations disease CGI
Entrez Id: 2064
Gene Symbol: ERBB2
ERBB2 		0.400 CausalMutation disease CGI