Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3084
Gene Symbol: NRG1
NRG1
0.330 Biomarker phenotype BEFREE Our study showed that modulation of Nrg1-ErbB signaling may have therapeutic value for treating pain symptoms in BPS/IC. 30989724 2019
Entrez Id: 3084
Gene Symbol: NRG1
NRG1
0.330 GeneticVariation phenotype BEFREE NRG1×DISC1 mutant mice were generated and adult mice from each genotype were assessed for pain sensitivity (hot plate and tail flick tests), anxiety (light-dark box), and stress-induced hypothermia. 27916686 2017
Entrez Id: 3084
Gene Symbol: NRG1
NRG1
0.330 Biomarker phenotype CTD_human At baseline, deletion of NRG1 and DISC1 each reduced thermal pain sensitivity, while deletion of COMT increased pain sensitivity. 20561508 2010
Entrez Id: 3084
Gene Symbol: NRG1
NRG1
0.330 Biomarker phenotype BEFREE Neuregulin 1 is a pronociceptive cytokine that is regulated by progesterone in the spinal cord: implications for sex specific pain modulation. 17459743 2008