Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 443
Gene Symbol: ASPA
ASPA
0.010 Biomarker disease BEFREE It is known, that ASP can cause several toxicities such as hypersensitivity, pancreatitis, as well as severe lipid and coagulation disturbances. 31515171 2019
Entrez Id: 259266
Gene Symbol: ASPM
ASPM
0.010 Biomarker disease BEFREE It is known, that ASP can cause several toxicities such as hypersensitivity, pancreatitis, as well as severe lipid and coagulation disturbances. 31515171 2019
Entrez Id: 59067
Gene Symbol: IL21
IL21
0.010 AlteredExpression disease BEFREE At the protein level, IL-21 was elevated in SAP patients compared with those with mild pancreatitis, although this was not significant. 30451792 2019
Entrez Id: 7432
Gene Symbol: VIP
VIP
0.010 Biomarker disease BEFREE Gastrin, cholecystokinin, and vasoactive intestinal peptide were significantly associated with chymotrypsin in all three statistical models and resulted in a 1.06, 1.98, and 2.74 times higher chymotrypsin level in alcohol-related pancreatitis, respectively. 30529016 2019
Entrez Id: 8431
Gene Symbol: NR0B2
NR0B2
0.010 Biomarker disease BEFREE Consequently, SHP-deficient mice also are more susceptible to cerulein-induced pancreatitis. 31296559 2019
Entrez Id: 9474
Gene Symbol: ATG5
ATG5
0.010 Biomarker disease BEFREE It is known, that ASP can cause several toxicities such as hypersensitivity, pancreatitis, as well as severe lipid and coagulation disturbances. 31515171 2019
Entrez Id: 4922
Gene Symbol: NTS
NTS
0.010 Biomarker disease BEFREE Here, we report the use of the <sup>68</sup>Ga-labeled neurotensin (NTS) analogue DOTA-NT-20.3 to image human PDAC in animal models and to discriminate tumors from pancreatitis. 31013092 2019
Entrez Id: 718
Gene Symbol: C3
C3
0.010 Biomarker disease BEFREE It is known, that ASP can cause several toxicities such as hypersensitivity, pancreatitis, as well as severe lipid and coagulation disturbances. 31515171 2019
Entrez Id: 3456
Gene Symbol: IFNB1
IFNB1
0.010 Biomarker disease BEFREE TLR3 Ligand PolyI:C Prevents Acute Pancreatitis Through the Interferon-β/Interferon-α/β Receptor Signaling Pathway in a Caerulein-Induced Pancreatitis Mouse Model. 31130960 2019
Entrez Id: 10267
Gene Symbol: RAMP1
RAMP1
0.010 Biomarker disease BEFREE Using a RAMP1 knockout-mouse (RAMP1<sup>-/-</sup>) we examined the role of the CGRP-receptor in the acute-phase of cerulein-induced pancreatitis. 31109903 2019
Entrez Id: 10630
Gene Symbol: PDPN
PDPN
0.010 Biomarker disease BEFREE Podoplanin (Th17 marker)-expressing lymphocytes were present in the lymphoid follicles of those with follicular pancreatitis, whereas these were absent in normal lymph nodes and in lymphoid follicles of those with IgG4-related autoimmune pancreatitis (AIP). 30515871 2019
Entrez Id: 7965
Gene Symbol: AIMP2
AIMP2
0.010 Biomarker disease BEFREE Inhibition of p38 activation resulted in alleviated pancreatitis. 31432106 2019
Entrez Id: 1398
Gene Symbol: CRK
CRK
0.010 Biomarker disease BEFREE Inhibition of p38 activation resulted in alleviated pancreatitis. 31432106 2019
Entrez Id: 434
Gene Symbol: ASIP
ASIP
0.010 Biomarker disease BEFREE It is known, that ASP can cause several toxicities such as hypersensitivity, pancreatitis, as well as severe lipid and coagulation disturbances. 31515171 2019
Entrez Id: 340061
Gene Symbol: STING1
STING1
0.010 AlteredExpression disease BEFREE Macrophages express STING and activate pancreatic inflammation in AP. 29425920 2018
Entrez Id: 8767
Gene Symbol: RIPK2
RIPK2
0.010 Biomarker disease BEFREE Thus, our identified RIPK2 inhibitor may offer possible therapeutic control of inflammation in diseases such as inflammatory bowel disease, asthma, cystic fibrosis, primary sclerosing cholangitis, and pancreatitis. 29555876 2018
Entrez Id: 9021
Gene Symbol: SOCS3
SOCS3
0.010 AlteredExpression disease BEFREE HSF1 can protect AR42J cells from cerulein-induced pancreatitis through inhibiting the expression of SOCS3. 29194340 2018
Entrez Id: 196
Gene Symbol: AHR
AHR
0.010 Biomarker disease BEFREE Interestingly, the AhR antagonist resveratrol, attenuated BaP-induced mitochondrial respiratory defects in the pancreas, and reversed pancreatitis, both histologically and biochemically in wild-type mice. 30165701 2018
Entrez Id: 22933
Gene Symbol: SIRT2
SIRT2
0.010 Biomarker disease BEFREE Loss of Sirt2 increases and prolongs a caerulein-induced pancreatitis permissive phenotype and induces spontaneous oncogenic Kras mutations in mice. 30405152 2018
Entrez Id: 7421
Gene Symbol: VDR
VDR
0.010 GeneticVariation disease BEFREE Single nucleotide polymorphisms (SNPs), Apa-1, Bsm-1, Fok-1, and Taq-1, in the vitamin D receptor gene (<i>VDR</i>) are known in various diseases, but not yet in pancreatitis. 29966312 2018
Entrez Id: 57862
Gene Symbol: ZNF410
ZNF410
0.010 Biomarker disease BEFREE Single nucleotide polymorphisms (SNPs), Apa-1, Bsm-1, Fok-1, and Taq-1, in the vitamin D receptor gene (<i>VDR</i>) are known in various diseases, but not yet in pancreatitis. 29966312 2018
Entrez Id: 3567
Gene Symbol: IL5
IL5
0.010 Biomarker disease BEFREE Mechanistically, we show that eosinophil-deficient GATA1 and endogenous IL-5-deficient mice were protected from the induction of proinflammatory and profibrotic cytokines, chemokines, tissue eosinophilia, and mast cells in a cerulein-induced murine model of pancreatitis. 28935682 2018
Entrez Id: 3852
Gene Symbol: KRT5
KRT5
0.010 Biomarker disease BEFREE β cells can be generated from cytokeratin 5-positive cells after cerulein-induced pancreatitis in adult mice. 29307825 2018
Entrez Id: 1026
Gene Symbol: CDKN1A
CDKN1A
0.010 Biomarker disease BEFREE Development of autoimmune pancreatitis is independent of CDKN1A/p21-mediated pancreatic inflammation. 28774888 2018
Entrez Id: 55850
Gene Symbol: USE1
USE1
0.010 Biomarker disease BEFREE Cannabis Use Is Associated With Increased Risk of Post-Endoscopic Retrograde Cholangiopancreatography Pancreatitis: Analysis of the US Nationwide Inpatient Sample Database, 2004-2014. 30134357 2018