Gene: PARK7 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 Biomarker disease CTD_human Effects of pharmacological agents on the lifespan phenotype of Drosophila DJ-1beta mutants. 20423725 2010
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease BEFREE Mutations of the DJ-1 (PARK7) gene are linked to familial Parkinson's disease. 15784737 2005
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 Biomarker disease LHGDN Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis. 15944198 2005
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 Biomarker disease LHGDN DJ-1/PARK7, a cancer- and Parkinson's disease (PD)-associated protein, protects cells from toxic stresses. 17015834 2006
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease BEFREE Mutations in the DJ-1 gene cause autosomal recessive early onset PD in two European families. 14713311 2003
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease LHGDN Molecular basis for the structural instability of human DJ-1 induced by the L166P mutation associated with Parkinson's disease. 18707128 2008
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease BEFREE DJ-1 (PARK7) is a gene linked to autosomal recessive Parkinson disease (PD). 24899725 2014
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease BEFREE Mutations in the DJ-1 gene have been implicated in the PARK7-linked autosomal recessive form of Parkinson's disease (PD). 15519239 2004
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease LHGDN [Association of the DJ-1 gene polymorphism with sporadic Parkinson's disease in Sichuan province of China]. 18841573 2008
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease BEFREE We characterized the pathophenotypes of dopaminergic neuronal cells that were deficient in PINK1 or DJ-1, genes with mutations linked to familial PD. 21664494 2011
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 Biomarker disease BEFREE DJ-1 - a causative agent of familial Parkinson's disease PARK7 - is responsible for inducing antioxidative reaction. 20202083 2010
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 Biomarker disease BEFREE Mutations in seven genes are robustly associated with autosomal dominant (SNCA, LRRK2, EIF4G1, VPS35) or recessive (parkin/PARK2, PINK1, DJ1/PARK7) Parkinson's disease (PD) or parkinsonism. 23462481 2013
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 Biomarker disease BEFREE Our aim was to examine the possibility of using DJ-1 (PARK7), as a novel therapeutic target for Parkinson's disease. 26024237 2015
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease LHGDN Genetics of Parkinson disease. 15717024 2004
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease LHGDN Novel homozygous p.E64D mutation in DJ1 in early onset Parkinson disease (PARK7). 15365989 2004
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease LHGDN L166P mutant DJ-1, causative for recessive Parkinson's disease, is degraded through the ubiquitin-proteasome system. 12851414 2003
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 Biomarker disease BEFREE Elucidating the physiological role of DJ-1 protein may promote understanding of the mechanisms of brain neuronal maintenance and pathogenesis of Parkinson's disease. 12446870 2003
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 Biomarker disease CTD_human Correlation between the biochemical pathways altered by mutated parkinson-related genes and chronic exposure to manganese. 25149416 2014
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 Biomarker disease BEFREE However, the causes of the emotional symptom accompanying PARK7-associated and other forms of Parkinson's disease remain largely unexplored. 31504219 2019
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease BEFREE DJ-1 (also known as PARK7) has been identified as a causal gene for hereditary recessive Parkinson's disease (PD). 28993701 2017
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 Biomarker disease BEFREE Loss-of-function of DJ-1 protein is suggested to contribute to the onset of PD, but the causes of DJ-1 dysfunction remain insufficiently elucidated. 28446034 2017
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 Biomarker disease BEFREE Here, DJ-1 (PARK7) gained major attention when a conserved cysteine residue with a putative role in oxidative stress sensing/protection was linked to PD. 30011180 2018
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 AlteredExpression disease BEFREE Heightened DJ-1 (Park7) expression is associated with a reduction in chemotherapeutic-induced cell death and poor prognosis in several cancers, whereas the loss of DJ-1 function is found in a subgroup of Parkinson disease associated with neuronal death. 21097510 2011
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 Biomarker disease BEFREE DJ-1 was initially identified by us as a novel oncogene and has recently been found to be a causative gene for familial Parkinson's disease PARK7. 16781058 2006
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 Biomarker disease BEFREE The DJ-1 gene is a causative gene for familial PD (park7) and also an oncogene. 23766857 2013