Gene: PARK7 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease BEFREE Mutations in the DJ-1 gene cause autosomal recessive early onset PD in two European families. 14713311 2003
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease LHGDN L166P mutant DJ-1, causative for recessive Parkinson's disease, is degraded through the ubiquitin-proteasome system. 12851414 2003
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 Biomarker disease BEFREE Elucidating the physiological role of DJ-1 protein may promote understanding of the mechanisms of brain neuronal maintenance and pathogenesis of Parkinson's disease. 12446870 2003
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease BEFREE Polymorphism in the human DJ-1 gene is not associated with sporadic dementia with Lewy bodies or Parkinson's disease. 14625045 2003
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease LHGDN Assessment of a DJ-1 (PARK7) polymorphism in Finnish PD. 14557580 2003
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease BEFREE Mutations in the DJ-1 gene have been implicated in the PARK7-linked autosomal recessive form of Parkinson's disease (PD). 15519239 2004
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease LHGDN Genetics of Parkinson disease. 15717024 2004
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease LHGDN Novel homozygous p.E64D mutation in DJ1 in early onset Parkinson disease (PARK7). 15365989 2004
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease BEFREE Mutations in the DJ-1 gene have recently been shown to cause autosomal recessive Parkinson's disease. 14707326 2004
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 Biomarker disease LHGDN An association study of four common polymorphisms in the DJ1 gene and Parkinson disease (PD) was conducted. 15304593 2004
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 Biomarker disease LHGDN Linking DJ-1 to neurodegeneration offers novel insights for understanding the pathogenesis of Parkinson's disease. 14712351 2004
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 Biomarker disease BEFREE Pathological properties of the Parkinson's disease-associated protein DJ-1 in alpha-synucleinopathies and tauopathies: relevance for multiple system atrophy and Pick's disease. 14991385 2004
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease LHGDN Analysis of an early-onset Parkinson's disease cohort for DJ-1 mutations. 15254937 2004
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease LHGDN Reduced anti-oxidative stress activities of DJ-1 mutants found in Parkinson's disease patients. 15219840 2004
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease BEFREE Our studies revealed that the Parkinson's disease-linked L166P mutation impaired the intrinsic folding propensity of DJ-1 protein, resulting in a spontaneously unfolded structure that was incapable of forming a homodimer with itself or a heterodimer with wild-type DJ-1. 14665635 2004
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease BEFREE An association study of four common polymorphisms in the DJ1 gene and Parkinson disease (PD) was conducted. 15304593 2004
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease LHGDN DJ-1 (PARK7) mutations are less frequent than Parkin (PARK2) mutations in early-onset Parkinson disease. 14872018 2004
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 Biomarker disease LHGDN Causes of Parkinson's disease: genetics of DJ-1. 15503154 2004
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease BEFREE Mutations in the PARK7/DJ-1 gene cause autosomal-recessive Parkinson's disease.In some patients the gene is deleted. 14607841 2004
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease BEFREE Mutations of the DJ-1 (PARK7) gene are linked to familial Parkinson's disease. 15784737 2005
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 Biomarker disease LHGDN Mitochondrial localization of the Parkinson's disease related protein DJ-1: implications for pathogenesis. 15944198 2005
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease BEFREE Parkin-mediated alterations in DJ-1 protein stability may be pathogenically relevant as DJ-1 levels are dramatically increased in the detergent-insoluble fraction from sporadic PD/DLB brains, but are reduced in the insoluble fraction from parkin-linked autosomal recessive juvenile-onset PD brains. 15525661 2005
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 Biomarker disease BEFREE The Parkinson's disease-associated DJ-1 protein is a transcriptional co-activator that protects against neuronal apoptosis. 15790595 2005
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 GeneticVariation disease BEFREE Both homozygous (L166P, M26I, deletion) and heterozygous mutations (D149A, A104T) in the DJ-1 gene have been identified in Parkinson's disease (PD) patients. 15944198 2005
Entrez Id: 11315
Gene Symbol: PARK7
PARK7 		0.600 Biomarker disease CTD_human Mutations of the DJ-1 (PARK7) gene are linked to familial Parkinson's disease. 15784737 2005