| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.600 | Biomarker | disease | CTD_human | Correlation between the biochemical pathways altered by mutated parkinson-related genes and chronic exposure to manganese. | 25149416 | 2014 | ||||
|
0.600 | Biomarker | disease | CTD_human | Parkinson disease protein DJ-1 binds metals and protects against metal-induced cytotoxicity. | 23792957 | 2013 | ||||
|
0.600 | Biomarker | disease | CTD_human | Loss-of-function mutations in the gene encoding the multifunctional protein, DJ-1, have been implicated in the pathogenesis of early-onset familial Parkinson's disease (PD), suggesting that DJ-1 may act as a neuroprotectant for dopaminergic (DA) neurons. | 22898350 | 2012 | ||||
|
0.600 | Biomarker | disease | CTD_human | DJ-1 was first identified as an activated ras-dependent oncogene and later found to be a causative gene for a familial form of Parkinson's disease, PARK7. | 23037695 | 2012 | ||||
|
0.600 | Biomarker | disease | CTD_human | Early exposure to paraquat sensitizes dopaminergic neurons to subsequent silencing of PINK1 gene expression in mice. | 22043175 | 2011 | ||||
|
0.600 | Biomarker | disease | CTD_human | Effects of pharmacological agents on the lifespan phenotype of Drosophila DJ-1beta mutants. | 20423725 | 2010 | ||||
|
0.600 | Biomarker | disease | CTD_human | Gene expression profiling of normal and SOD2 deficient erythroblasts identified the Parkinson's disease locus DJ-1 (Park7) as a differentially expressed transcript. | 20800516 | 2010 | ||||
|
0.600 | Biomarker | disease | CTD_human | Mitochondria mass is low in mouse substantia nigra dopamine neurons: implications for Parkinson's disease. | 17010972 | 2007 | ||||
|
0.600 | Biomarker | disease | CTD_human | Mutations of the DJ-1 (PARK7) gene are linked to familial Parkinson's disease. | 15784737 | 2005 |