Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1
0.100 Biomarker disease BEFREE Clinical examination included MDS-Unified Parkinson Disease Rating Scale part III, Mini Mental State Examination, and Montreal Cognitive Assessment. 31725927 2020
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1
0.100 Biomarker disease BEFREE Accuracy of MDS-UPDRS section IV for detecting motor fluctuations in Parkinson's disease. 30737581 2019
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1
0.100 Biomarker disease BEFREE While levodopa dose (SMD = 0.05, 95% CI: -0.09 -0.19,P = 0.48), Hoehn and Yahr stage(H & Y stage) (SMD =-0.05, 95% CI: -0.14 - 0.04,P = 0.27), MDS-UPDRS Part III score(UPDRS III score) (SMD =-0.05, 95% CI: -0.13 - 0.03,P = 0.24), PD duration (SMD =-0.23, 95% CI: 0.10 - 0.37,P < 0.01)and Mini-Mental Status Examination score (MMSE score) (SMD = 0.10, 95% CI: -0.11 - 0.31,P = 0.33)were not related with PD-ICDs+. 31167116 2019
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1
0.100 Biomarker disease BEFREE Does the MDS-UPDRS provide the precision to assess progression in early Parkinson's disease? Learnings from the Parkinson's progression marker initiative cohort. 31073716 2019
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1
0.100 GeneticVariation disease BEFREE People with Parkinson's disease underwent a battery of clinical assessments to evaluate symptom severity, including motor (MDS-UPDRS) and cognitive (ACE-R) assessments. 31275543 2019
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1
0.100 Biomarker disease BEFREE Our study evidenced that 12 weeks of probiotic consumption by individuals with PD had useful impacts on MDS-UPDRS and few metabolic profiles. 29891223 2019
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1
0.100 Biomarker disease BEFREE In addition to this scale, the following measures were applied: MDS-Unified Parkinson's Disease Rating Scale, Mini-Mental State Examination, Frontal Assessment Behavior, and Ardouin Scale of Behavior in Parkinson's Disease (ASBPD). 30862454 2019
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1
0.100 Biomarker disease BEFREE In particular, medical specialists refer to the MDS-UPDRS (Movement Disorder Society - sponsored revision of Unified Parkinson's Disease Rating Scale) that is the most widely used clinical scale for PD rating. 31830986 2019
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1
0.100 GeneticVariation disease BEFREE Baseline clinical, CSF, and imaging measures in early PD predicted change in MDS-UPDRS and dopamine-transporter binding, but the predictive value of the models was low. 31450510 2019
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1
0.100 GeneticVariation disease BEFREE We present a 48-year-old woman with Parkinson's disease in whom carbidopa was added to Mucuna pruriens, resulting in marked motor improvement (documented on video and using MDS-UPDRS motor scores). 30856121 2019
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1
0.100 GeneticVariation disease BEFREE Data were obtained from the Parkinson's Progression Markers Initiative cohort and included repeated MDS-UPDRS measurements from 423 de novo Parkinson's disease patients (median follow-up: 54 months). 31291488 2019
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1
0.100 AlteredExpression disease BEFREE We evaluated the relationship between conventional measures of disease and motor severity (e.g., MDS-UPDRS part III), laboratory-based measures of gait and balance, and daily-living physical activity measures in patients with PD. 30718220 2019
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1
0.100 Biomarker disease BEFREE In this work, a fuzzy inference model to evaluate hands pronation/supination exercises during the MDS-UPDRS motor examination is proposed to analyze different extracted features from the bio-mechanical signals acquired from patients with Parkinson's disease (PD) in different stages of severity. 29042162 2018
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1
0.100 Biomarker disease BEFREE The total MDS-UPDRS for PD was 32.4 compared to 4.6 for HC and 28.2 for SWEDD. 30564614 2018
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1
0.100 Biomarker disease BEFREE We present 5-year longitudinal data on the change of the MDS-UPDRS and other clinical and dopamine transporter imaging outcome measures in early PD. 29572948 2018
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1
0.100 GeneticVariation disease BEFREE AChE: acetylcholinesterase; AD: Alzheimer disease; DLB: dementia with Lewy bodies; ET: essential tremor; MDS-UPDRS: Movement Disorder Society-sponsored Unified Parkinson's Disease Rating Scale; MMSE: Mini-Mental State Examination; PD: Parkinson disease; PDD: Parkinson disease dementia. 28911255 2018
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1
0.100 GeneticVariation disease BEFREE Moreover, PD-Monitor scores in 97 PD patients with MDS-UPDRS FT bradykinesia and each PD subgroup (FT bradykinesia scored from 1 to 3) were all higher than that in NC. 30147869 2018
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1
0.100 GeneticVariation disease BEFREE The striatal binding ratio was associated with PD risk estimates (P = .040), University of Pennsylvania Smell Identification Test (P = .002), Rapid Eye Movement Sleep Behavior Disorder Screening Questionnaire scores (P = .024), tapping speed (P = .024), and MDS-UPDRS motor scores (P = .009). 29380907 2018
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1
0.100 GeneticVariation disease BEFREE Correlations of clinical variables (i.e., PDQ-39 quality of life and MDS-UPDRS) with ALFF values were examined for the exercise-trained PD participants. 29273705 2017
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1
0.100 Biomarker disease BEFREE Changes in MDS-UPDRS and UDysRS confirm that LCIG treatment can efficiently improve experiences of daily living in advanced PD. 28185758 2017
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1
0.100 Biomarker disease BEFREE This study presents a framework for analyzing MDS-UPDRS data, which can be adapted to more traditional UPDRS data collected in PD clinical trials and result in more efficient designs and analyses of such studies. 28247193 2017
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1
0.100 Biomarker disease BEFREE Extended-TUG time was significantly correlated to MDS-UPDRS III score and to SCOPA-Cog, ACE-R (p<0.001) and PDQ-39 scores (p<0.01). 28320196 2017
Entrez Id: 5048
Gene Symbol: PAFAH1B1
PAFAH1B1
0.100 Biomarker disease BEFREE The association of RBD, autonomic symptoms, and MDS-UPDRS Part II scores with psychosis underscore its link to brainstem dysfunction and greater PD motor symptom severity. 28735797 2017