| Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|
|
0.070 | GeneticVariation | disease | BEFREE | MDR1 gene C3435T polymorphism enacts an important role on colchicine response in FMF; good response to colchicine treatment was related to the C allele, whereas poor response was related to the T allele in FMF. | 24180297 | 2014 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | The aim of this study was to perform genotyping and haplotyping analysis of the multidrug resistance (ATP-binding cassette, subfamily B, member 1 - ABCB1) gene in FMF patients.2. | 24773260 | 2014 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | No significant relationship was found between colchicine doses that would introduce optimal clinical response and affect the therapeutic dose and CYP3A4 and P-gp/MDR1 gene polymorphisms in these FMF patients. | 23408444 | 2013 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | Our results indicate that C3435T polymorphism in exon 26 of MDR1 gene is associated with colchicine resistance in nonresponder FMF patients during the common therapy protocol. | 21851199 | 2011 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | Analysis of common MDR1 (ABCB1) gene C1236T and C3435T polymorphisms in Turkish patients with familial Mediterranean fever. | 22194207 | 2011 | ||||
|
0.070 | GeneticVariation | disease | BEFREE | We investigated the association between MDR1 3435C to T polymorphism and colchicine response in patients with FMF. | 17610314 | 2007 | ||||
|
0.070 | Biomarker | disease | BEFREE | Does the lack of the P-glycoprotein efflux pump in neutrophils explain the efficacy of colchicine in familial Mediterranean fever and other inflammatory diseases? | 9848464 | 1998 |