|
CDKN2B-AS1
|
0.090 |
AlteredExpression
|
disease |
BEFREE |
The upregulation of CDKN2BAS, a long noncoding RNA gene expression in gingival epithelial cells and gingival fibroblasts of periodontitis shows a strong correlation between the severity of atherosclerosis and PD.
|
31173806 |
2019 |
|
CDKN2B-AS1
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
The primary objectives of the study were to assess, among cardiovascular (CV angiographically proven ≥50% stenosis of a main coronary artery) patients, the impact of ANRIL SNPs rs133049 and rs3217992 on the severity of periodontitis and the previous history of coronary events, as well as on the occurrence of further adverse CV events.
|
29732560 |
2018 |
|
CDKN2B-AS1
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
This study is the first to show that, in addition to gender and BMI, also a leading SNP in ANRIL is explanatory for inter-individual variation in hsCRP levels in periodontitis patients of North European descent.
|
26348353 |
2015 |
|
CDKN2B-AS1
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
Genetic studies demonstrated the presence of risk alleles in the genes ANRIL and CAMTA1/VAMP3 that are shared between coronary artery disease (CAD) and periodontitis.
|
25466412 |
2015 |
|
CDKN2B-AS1
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
However, susceptibility genes, such as CDKN2BAS (Cyclin Dependend KiNase 2B AntiSense RNA; alias ANRIL [ANtisense Rna In the Ink locus]), glycosyltransferase 6 domain containing 1 (GLT6D1) and cyclooxygenase 2 (COX2), have been reported as conclusive risk loci of periodontitis.
|
24528298 |
2014 |
|
CDKN2B-AS1
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
Recent studies showed a correlation of decreased concentrations of proximal ANRIL transcripts with homozygous carriership of the CAD and PD main risk alleles.
|
23813974 |
2013 |
|
CDKN2B-AS1
|
0.090 |
Biomarker
|
disease |
BEFREE |
ANRIL is associated with periodontitis across different populations.
|
23587006 |
2013 |
|
CDKN2B-AS1
|
0.090 |
Biomarker
|
disease |
BEFREE |
CDKN2BAS is associated with periodontitis in different European populations and is activated by bacterial infection.
|
20978019 |
2011 |
|
CDKN2B-AS1
|
0.090 |
GeneticVariation
|
disease |
BEFREE |
Elucidation of the interplay of ANRIL transcript variants and their involvement in increased susceptibility to the interactive diseases CHD and periodontitis promises new insight into the underlying shared pathogenic mechanisms of these complex common diseases.
|
19214202 |
2009 |
|
CDKN2B-AS1
|
0.090 |
GeneticVariation
|
disease |
LHGDN |
Elucidation of the interplay of ANRIL transcript variants and their involvement in increased susceptibility to the interactive diseases CHD and periodontitis promises new insight into the underlying shared pathogenic mechanisms of these complex common diseases.
|
19214202 |
2009 |