Gene: PTGS2 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.050 Biomarker disease BEFREE Polyps in PJS patients and in Lkb1(+/-) mice that model PJS polyposis are frequently characterized by elevated cyclooxygenase-2 (COX-2). 15480979 2004
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.050 AlteredExpression disease BEFREE Selective COX-2 overexpression was noted in hamartomatous polyp tissue from PJS individuals. 12650805 2003
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.050 AlteredExpression disease BEFREE The presence of COX-2 expression in PJS carcinomas and dysplastic hamartomas provides a rationale for chemoprevention with nonsteroidal anti-inflammatory drugs or COX-2 inhibitors. 12912958 2003
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.050 Biomarker disease BEFREE These results suggest that COX-2 plays a role in tumorigenesis in PJS and may therefore be considered as a potential target for PJS chemoprevention. 14623934 2003
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.050 Biomarker disease BEFREE These findings thereby identify COX-2 as a potential target for chemoprevention in PJS patients. 12218179 2002