Concerning anxiety disorders and alcohol use disorders, the current findings are preliminary and need further verification to explain the association of ARNTL2, being suggestive only, with social phobia (rs2306073) and with alcohol abuse (rs7958822, rs4964057).
Single nucleotide polymorphisms in two genes showed some evidence for association to social phobia: in ARNTL2rs2306073 (p = .0099) and in DRD2 rs7131056 (p = .0084).