Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.100 Biomarker group BEFREE Presence of pleural effusion is associated with a poor prognosis in patients with epidermal growth factor receptor-mutated lung cancer receiving tyrosine kinase inhibitors as first-line treatment. 28124437 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.100 GeneticVariation group BEFREE Pleural effusion may serve as a less invasive sample for EGFR mutation detection. 28787267 2017
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.100 GeneticVariation group BEFREE Our data revealed novel lipid candidate markers in the non-cellular fraction of PE that holds potential to aid the diagnosis of benign, EGFR mutation positive and negative NSCLC. 27739449 2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.100 GeneticVariation group BEFREE This study disclosed associations between CT features and alterations of EGFR (air bronchogram, pleural retraction, small lesion size, absence of fibrosis), ALK (pleural effusion) and KRAS (round lesion shape, nodules in non-tumour lobes). 25956936 2016
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.100 Biomarker group BEFREE VEGF and EGFR play important roles in the formation of pleural effusion. 25635424 2015
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.100 GeneticVariation group BEFREE Though the possibility of using malignant pleural effusions (MPEs) as alternatives for metastatic pleural tumor tissues (MPTTs) in epidermal growth factor receptor (EGFR) mutation test has been examined, due to the lack of studies comparing the results in matching MPEs and MPTTs, the clinical value of MPEs for advanced adenocarcinoma patients with pleural effusions is not confirmed. 24587142 2014
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.100 GeneticVariation group BEFREE The results established the important role of HRM as a reliable and efficient method to determine EGFR mutation status and indicated the feasibility of using pleural effusion in replacement of biopsy tissues in particular clinical cases. 25674250 2014
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.100 GeneticVariation group BEFREE Cytology samples including fine needle aspirate and pleural effusion can be used successfully to determine EGFR mutation status provided that sensitive testing methods are employed. 23172555 2013
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.100 GeneticVariation group BEFREE The diagnostic accuracy of pleural effusion and plasma samples versus tumour tissue for detection of EGFR mutation in patients with advanced non-small cell lung cancer: comparison of methodologies. 23888061 2013
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.100 GeneticVariation group BEFREE Prediction of epidermal growth factor receptor mutations in the plasma/pleural effusion to efficacy of gefitinib treatment in advanced non-small cell lung cancer. 20155428 2010
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.100 GeneticVariation group BEFREE EGFR mutations were detected by both DHPLC procedure and direct sequencing using lung cancer tissue samples obtained from 97 patients (81 surgical specimens and 16 pleural effusions of non-resectable lung cancer patients). 16947044 2007
Entrez Id: 1956
Gene Symbol: EGFR
EGFR
0.100 GeneticVariation group BEFREE High sensitivity detection of epidermal growth factor receptor mutations in the pleural effusion of non-small cell lung cancer patients. 16827805 2006
Entrez Id: 114548
Gene Symbol: NLRP3
NLRP3
0.100 GeneticVariation group CLINVAR
Entrez Id: 101928376
Gene Symbol: IL12A-AS1
IL12A-AS1
0.100 Biomarker group HPO
Entrez Id: 51752
Gene Symbol: ERAP1
ERAP1
0.100 Biomarker group HPO
Entrez Id: 5781
Gene Symbol: PTPN11
PTPN11
0.100 CausalMutation group CLINVAR
Entrez Id: 2859
Gene Symbol: GPR35
GPR35
0.100 Biomarker group HPO
Entrez Id: 5644
Gene Symbol: PRSS1
PRSS1
0.100 Biomarker group HPO
Entrez Id: 650
Gene Symbol: BMP2
BMP2
0.100 Biomarker group HPO
Entrez Id: 4210
Gene Symbol: MEFV
MEFV
0.100 Biomarker group HPO
Entrez Id: 5645
Gene Symbol: PRSS2
PRSS2
0.100 Biomarker group HPO
Entrez Id: 144811
Gene Symbol: LACC1
LACC1
0.100 Biomarker group HPO
Entrez Id: 4179
Gene Symbol: CD46
CD46
0.100 Biomarker group HPO
Entrez Id: 596
Gene Symbol: BCL2
BCL2
0.100 Biomarker group HPO
Entrez Id: 720
Gene Symbol: C4A
C4A
0.100 Biomarker group HPO