Gene | Score gda | Association Type | Type | Original DB | Sentence supporting the association | PMID | PMID Year | ||||
---|---|---|---|---|---|---|---|---|---|---|---|
|
0.270 | AlteredExpression | disease | BEFREE | To explore whether the inhibition of MK2 activation has the same effect in experimental animals, MMI-0100, a peptide-mediated inhibitor of MK2, was used to verify whether MMI-0100 can ameliorate lung inflammation in a mouse model of ARDS by reducing endothelial expression of ICAM-1. | 30587921 | 2018 | ||||
|
0.270 | Biomarker | disease | BEFREE | Intercellular adhesion molecule-1 (ICAM-1) is known to play a key role in lung inflammation. | 30007888 | 2018 | ||||
|
0.270 | AlteredExpression | disease | BEFREE | Severity of lung inflammation was evaluated by white blood cell and differential count in BALF, and protein expression of inducible nitric oxide synthase (iNOS), intercellular adhesion molecule-1 (ICAM-1), tumor necrosis factor-α (TNF-α), matrix metalloproteinase-9 (MMP-9), and mRNA expression of nuclear factor-κB (NF-κB) in the lung. | 28747201 | 2017 | ||||
|
0.270 | Therapeutic | disease | RGD | Low-level laser therapy restores the oxidative stress balance in acute lung injury induced by gut ischemia and reperfusion. | 22882462 | 2013 | ||||
|
0.270 | Biomarker | disease | BEFREE | An anti-human ICAM-1 antibody inhibits rhinovirus-induced exacerbations of lung inflammation. | 23935498 | 2013 | ||||
|
0.270 | Biomarker | disease | BEFREE | Intercellular adhesion molecule-1-deficient mice show impaired lymphocyte recruitment to the lung, less airway hyper-responsiveness and less lung inflammation than healthy controls. | 16625213 | 2006 | ||||
|
0.270 | Biomarker | disease | BEFREE | Role of alveolar epithelial ICAM-1 in lipopolysaccharide-induced lung inflammation. | 12108870 | 2002 | ||||
|
0.270 | Biomarker | disease | BEFREE | Intercellular adhesion molecule 1 knockout abrogates radiation induced pulmonary inflammation. | 9177235 | 1997 |