Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5141
Gene Symbol: PDE4A
PDE4A
0.040 AlteredExpression disease BEFREE We studied the activity of a novel PDE4 inhibitor, CHF6001, both <i>in vitro</i> in human cells and <i>in vivo</i>, using bioluminescence imaging (BLI) in mice lung inflammation. 31798449 2019
Entrez Id: 5141
Gene Symbol: PDE4A
PDE4A
0.040 Biomarker disease BEFREE The aim of the present study was to investigate the role of the cyclic phosphodiesterase type 4 (PDE4) in human lung and to determine the effects of NCS 613, a new PDE4 inhibitor, on lung inflammation and bronchial hyperresponsiveness. 21784969 2011
Entrez Id: 5141
Gene Symbol: PDE4A
PDE4A
0.040 Biomarker disease BEFREE A multi-target antisense approach against PDE4 and PDE7 reduces smoke-induced lung inflammation in mice. 19457265 2009
Entrez Id: 5141
Gene Symbol: PDE4A
PDE4A
0.040 Biomarker disease BEFREE Thus, PDE4 inhibitors might ease AHR, but are unlikely to attenuate lung inflammation and atopy associated with childhood allergic asthma. 19596983 2009