Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.510 Biomarker group CTD_human Peripartum cardiomyopathy: analysis of clinical outcome, left ventricular function, plasma levels of cytokines and Fas/APO-1. 10716473 2000
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.510 Therapeutic group RGD Antioxidants and tumor necrosis factor alpha-inhibiting activity of sesame oil against doxorubicin-induced cardiotoxicity. 24441175 2014
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.510 GeneticVariation group BEFREE T-cells from CHF patients showed enhanced gene expression of chemokines, ligands in the tumor necrosis factor superfamily, as well as the inflammatory cytokines interferon-gamma and interleukin-18 with similar pattern in ischemic (n=5) and idiopathic cardiomyopathy (n=9). 14522416 2003
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3 		0.310 Biomarker group BEFREE TNNI3 is the third most important disease gene in this cohort and complete loss of TNNI3 leads to severe pediatric CMP. 31568572 2019
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.310 Therapeutic group CTD_human Type 5 adenylyl cyclase increases oxidative stress by transcriptional regulation of manganese superoxide dismutase via the SIRT1/FoxO3a pathway. 23536361 2013
Entrez Id: 6648
Gene Symbol: SOD2
SOD2 		0.310 GeneticVariation group BEFREE To reveal genetic risk factors of nonfamilial idiopathic cardiomyopathy (IDC) in Japanese, polymorphisms in the SOD2 and HLA-DRB1 genes were investigated in 86 patients and 380 healthy controls. 10425186 1999
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3 		0.310 Biomarker group CTD_human In vitro and in vivo examination of cardiac troponins as biochemical markers of drug-induced cardiotoxicity. 17587482 2007
Entrez Id: 5581
Gene Symbol: PRKCE
PRKCE 		0.300 Biomarker group CTD_human Protein kinase Cepsilon overexpression alters myofilament properties and composition during the progression of heart failure. 15242976 2004
Entrez Id: 1431
Gene Symbol: CS
CS 		0.300 Biomarker group CTD_human Time-dependent and tissue-specific accumulation of mtDNA and respiratory chain defects in chronic doxorubicin cardiomyopathy. 14568902 2003
Entrez Id: 111
Gene Symbol: ADCY5
ADCY5 		0.300 Biomarker group CTD_human "Adenylyl cyclase 5: a new clue in the search for the ""fountain of youth""?" 18029912 2007
Entrez Id: 2056
Gene Symbol: EPO
EPO 		0.300 Therapeutic group CTD_human Erythropoietin protects against doxorubicin-induced cardiomyopathy via a phosphatidylinositol 3-kinase-dependent pathway. 17928571 2008
Entrez Id: 355
Gene Symbol: FAS
FAS 		0.300 Biomarker group CTD_human Myocardial Fas ligand expression increases susceptibility to AZT-induced cardiomyopathy. 17943461 2007
Entrez Id: 6444
Gene Symbol: SGCD
SGCD 		0.300 Biomarker group CTD_human Hydrogen gas attenuates embryonic gene expression and prevents left ventricular remodeling induced by intermittent hypoxia in cardiomyopathic hamsters. 25281567 2014
Entrez Id: 5743
Gene Symbol: PTGS2
PTGS2 		0.300 Biomarker group CTD_human Nuclear factor-kappaB mediates over-expression of cyclooxygenase-2 during activation of RAW 264.7 macrophages in selenium deficiency. 11978490 2002
Entrez Id: 3688
Gene Symbol: ITGB1
ITGB1 		0.300 Biomarker group CTD_human Combined deficiency of dystrophin and beta1 integrin in the cardiac myocyte causes myocardial dysfunction, fibrosis and calcification. 18340010 2008
Entrez Id: 5600
Gene Symbol: MAPK11
MAPK11 		0.300 Therapeutic group CTD_human Cocaine and apoptosis in myocardial cells. 10620750 1999
Entrez Id: 554
Gene Symbol: AVPR2
AVPR2 		0.300 Biomarker group CTD_human Upregulation of vasopressin V2 and aquaporin 2 in the inner medullary collecting duct of cardiomyopathic hamsters is attenuated by enalapril treatment. 12145768 2002
Entrez Id: 356
Gene Symbol: FASLG
FASLG 		0.300 Biomarker group CTD_human Myocardial Fas ligand expression increases susceptibility to AZT-induced cardiomyopathy. 17943461 2007
Entrez Id: 2056
Gene Symbol: EPO
EPO 		0.300 Therapeutic group CTD_human Preventive cardioprotection of erythropoietin against doxorubicin-induced cardiomyopathy. 17924179 2007
Entrez Id: 7097
Gene Symbol: TLR2
TLR2 		0.300 Biomarker group CTD_human Modulation of doxorubicin-induced cardiac dysfunction in toll-like receptor-2-knockout mice. 15505089 2004
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		0.300 Biomarker group CTD_human Increased plasma endothelin-1 and cardiac nitric oxide during doxorubicin-induced cardiomyopathy. 11589785 2001
Entrez Id: 2056
Gene Symbol: EPO
EPO 		0.300 Therapeutic group CTD_human Erythropoietin improves myocardial performance in doxorubicin-induced cardiomyopathy. 16731534 2006
Entrez Id: 9997
Gene Symbol: SCO2
SCO2 		0.300 Biomarker group CTD_human Retrospective, multicentric study of 180 children with cytochrome C oxidase deficiency. 16326995 2006
Entrez Id: 1756
Gene Symbol: DMD
DMD 		0.300 Therapeutic group CTD_human Intolerance to ß-blockade in a mouse model of δ-sarcoglycan-deficient muscular dystrophy cardiomyopathy. 20675662 2010
Entrez Id: 551
Gene Symbol: AVP
AVP 		0.300 Biomarker group CTD_human Upregulation of vasopressin V2 and aquaporin 2 in the inner medullary collecting duct of cardiomyopathic hamsters is attenuated by enalapril treatment. 12145768 2002