Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3458
Gene Symbol: IFNG
IFNG 		0.210 Biomarker group MGD
Entrez Id: 4035
Gene Symbol: LRP1
LRP1 		0.200 Biomarker group MGD
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A 		0.200 Biomarker group MGD
Entrez Id: 2180
Gene Symbol: ACSL1
ACSL1 		0.200 Biomarker group MGD
Entrez Id: 1674
Gene Symbol: DES
DES 		0.200 Biomarker group MGD
Entrez Id: 111
Gene Symbol: ADCY5
ADCY5 		0.300 Biomarker group CTD_human "Adenylyl cyclase 5: a new clue in the search for the ""fountain of youth""?" 18029912 2007
Entrez Id: 7533
Gene Symbol: YWHAH
YWHAH 		0.300 Therapeutic group CTD_human 14-3-3 protein regulates Ask1 signaling and protects against diabetic cardiomyopathy. 18342293 2008
Entrez Id: 4217
Gene Symbol: MAP3K5
MAP3K5 		0.300 Biomarker group CTD_human 14-3-3 protein regulates Ask1 signaling and protects against diabetic cardiomyopathy. 18342293 2008
Entrez Id: 10879
Gene Symbol: SMR3B
SMR3B 		0.010 Biomarker group BEFREE PRL-3, a protein tyrosine phosphatase, was identified in a cDNA library from an explanted human heart obtained from a patient with idiopathic cardiomyopathy. 11355880 2001
Entrez Id: 11156
Gene Symbol: PTP4A3
PTP4A3 		0.010 Biomarker group BEFREE PRL-3, a protein tyrosine phosphatase, was identified in a cDNA library from an explanted human heart obtained from a patient with idiopathic cardiomyopathy. 11355880 2001
Entrez Id: 3920
Gene Symbol: LAMP2
LAMP2 		0.010 GeneticVariation group BEFREE LAMP2 mutations typically cause multisystem glycogen-storage disease (Danon's disease) but can also present as a primary cardiomyopathy. 15673802 2005
Entrez Id: 6901
Gene Symbol: TAZ
TAZ 		0.010 GeneticVariation group BEFREE TAZ mutations were found in 4/114 (3.5%) male patients with primary cardiomyopathy. 28183324 2017
Entrez Id: 4625
Gene Symbol: MYH7
MYH7 		0.010 Biomarker group BEFREE MYH7-related disease (MRD) is the most common hereditary primary cardiomyopathy (CM), with pathogenic MYH7 variants accounting for approximately 40% of familial hypertrophic CMs. 30588760 2019
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3 		0.310 Biomarker group BEFREE TNNI3 is the third most important disease gene in this cohort and complete loss of TNNI3 leads to severe pediatric CMP. 31568572 2019
Entrez Id: 4607
Gene Symbol: MYBPC3
MYBPC3 		0.300 Biomarker group CTD_human A common MYBPC3 (cardiac myosin binding protein C) variant associated with cardiomyopathies in South Asia. 19151713 2009
Entrez Id: 165904
Gene Symbol: XIRP1
XIRP1 		0.010 AlteredExpression group BEFREE Abnormal CMYA1 expression may be involved in cardiac dysplasia and primary cardiomyopathy. 29176328 2017
Entrez Id: 624
Gene Symbol: BDKRB2
BDKRB2 		0.300 Biomarker group CTD_human Altered baroreflex control of heart rate in bradykinin B2-receptor knockout mice. 10614985 1999
Entrez Id: 4842
Gene Symbol: NOS1
NOS1 		0.200 Biomarker group RGD Altered contractile response due to increased beta3-adrenoceptor stimulation in diabetic cardiomyopathy: the role of nitric oxide synthase 1-derived nitric oxide. 17721248 2007
Entrez Id: 5138
Gene Symbol: PDE2A
PDE2A 		0.200 Biomarker group RGD An abnormal gene expression of the beta-adrenergic system contributes to the pathogenesis of cardiomyopathy in cirrhotic rats. 19003918 2008
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		0.200 Biomarker group RGD Anti-inflammatory effects of atorvastatin improve left ventricular function in experimental diabetic cardiomyopathy. 17589825 2007
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.510 Therapeutic group RGD Antioxidants and tumor necrosis factor alpha-inhibiting activity of sesame oil against doxorubicin-induced cardiotoxicity. 24441175 2014
Entrez Id: 156
Gene Symbol: GRK2
GRK2 		0.300 Therapeutic group CTD_human Cardiac-specific ablation of G-protein receptor kinase 2 redefines its roles in heart development and beta-adrenergic signaling. 17008600 2006
Entrez Id: 116
Gene Symbol: ADCYAP1
ADCYAP1 		0.300 Therapeutic group CTD_human Cardioprotective effect of endogenous pituitary adenylate cyclase-activating polypeptide on Doxorubicin-induced cardiomyopathy in mice. 20378996 2010
Entrez Id: 3565
Gene Symbol: IL4
IL4 		0.300 Biomarker group CTD_human Cardiotoxicity and cardioprotection during chemotherapy. 7578376 1995
Entrez Id: 467
Gene Symbol: ATF3
ATF3 		0.300 Therapeutic group CTD_human Characterization of the regulatory mechanisms of activating transcription factor 3 by hypertrophic stimuli in rat cardiomyocytes. 25136830 2014