Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
0.400 Biomarker group BEFREE It is therefore possible that polymorphisms in the androgen synthesis gene 5alpha-reductase type II (SRD5A2) may be involved in the progression of prostate tumors. 19215786 2009
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
0.400 Biomarker group BEFREE DNA methylation screening of primary prostate tumors identifies SRD5A2 and CYP11A1 as candidate markers for assessing risk of biochemical recurrence. 26332453 2015
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
0.400 GeneticVariation group BEFREE Association of SRD5A2 genotype and pathological characteristics of prostate tumors. 10749132 2000
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
0.400 GeneticVariation group BEFREE We sequenced 26 matched human prostate tumor and constitutional DNA samples for somatic alterations in the SRD5A2, HPRT, and HSD3B2 genes, and identified 71 nucleotide substitutions. 18623241 2009
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
0.400 Biomarker group CTD_human Systematic replication study of reported genetic associations in prostate cancer: Strong support for genetic variation in the androgen pathway. 16998812 2006
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
0.400 Biomarker group CTD_human The interaction of CYP3A5 polymorphisms along the androgen metabolism pathway in prostate cancer. 18306354 2008
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
0.400 Biomarker group CTD_human SRD5A2 and HSD3B2 polymorphisms are associated with prostate cancer risk and aggressiveness. 17823934 2007
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
0.400 Biomarker group CTD_human [Dutasteride in the treatment of hormone refractory prostate cancer]. 18500220 2008
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
0.400 Biomarker group CTD_human 5alpha-Reductase type 2 gene variant associations with prostate cancer risk, circulating hormone levels and androgenetic alopecia. 17136762 2007
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
0.400 GeneticVariation group LHGDN 5alpha-Reductase type 2 gene variant associations with prostate cancer risk, circulating hormone levels and androgenetic alopecia. 17136762 2007
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
0.400 GeneticVariation group LHGDN Polymorphic markers in the 5alpha-reductase type II gene and the incidence of prostate cancer. 12712437 2003
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
0.400 GeneticVariation group LHGDN Evaluation of SRD5A2 sequence variants in susceptibility to hereditary and sporadic prostate cancer. 12746845 2003
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
0.400 AlteredExpression group LHGDN The loss of 5alpha-reductase type I and type II mRNA expression in metastatic prostate cancer to bone and lymph node metastasis. 12738739 2003
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
0.400 GeneticVariation group LHGDN No association between the SRD5A2 gene A49T missense variant and prostate cancer risk: lessons learned. 18469342 2008
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
0.400 GeneticVariation group LHGDN Association of V89L SRD5A2 polymorphism with prostate cancer development in a Japanese population. 12771801 2003
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
0.400 GeneticVariation group LHGDN 5alpha-reductase 2 polymorphisms as risk factors in prostate cancer. 12042668 2002
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
0.400 GeneticVariation group LHGDN It is therefore possible that polymorphisms in the androgen synthesis gene 5alpha-reductase type II (SRD5A2) may be involved in the progression of prostate tumors. 19215786 2009
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
0.400 GeneticVariation group LHGDN V89L polymorphism of the 5alpha-reductase Type II gene (SRD5A2), endogenous sex hormones, and prostate cancer risk. 18268111 2008
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
0.400 GeneticVariation group LHGDN Polymorphisms in the androgen receptor and type II 5 alpha-reductase genes and prostate cancer prognosis. 12210487 2002
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
0.400 AlteredExpression group LHGDN Decreased gene expression of steroid 5 alpha-reductase 2 in human prostate cancer: implications for finasteride therapy of prostate carcinoma. 12949937 2003
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
0.400 GeneticVariation group LHGDN SRD5A2 and HSD3B2 polymorphisms are associated with prostate cancer risk and aggressiveness. 17823934 2007
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
0.400 GeneticVariation group LHGDN Serum sex steroid hormone levels and polymorphisms of CYP17 and SRD5A2: implication for prostate cancer risk. 15477877 2004
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
0.400 GeneticVariation group LHGDN Low-activity V89L variant in SRD5A2 is associated with aggressive prostate cancer risk: an explanation for the adverse effects observed in chemoprevention trials using 5-alpha-reductase inhibitors. 17448593 2007
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
0.400 Biomarker group LHGDN Associations between polymorphisms in the steroid 5-alpha reductase type II (SRD5A2) gene and benign prostatic hyperplasia and prostate cancer. 16018939 2005
Entrez Id: 6716
Gene Symbol: SRD5A2
SRD5A2
0.400 AlteredExpression group LHGDN Differential alterations in 5alpha-reductase type 1 and type 2 levels during development and progression of prostate cancer. 15538746 2005