Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
0.400 Biomarker group CTD_human Genetic polymorphisms in IGF-I and IGFBP-3 are associated with prostate cancer in the Chinese population. 24586243 2014
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
0.400 Therapeutic group CTD_human Genetic polymorphisms in IGF-I and IGFBP-3 are associated with prostate cancer in the Chinese population. 24586243 2014
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
0.400 Biomarker group BEFREE Here we show that mice that are genetically deficient in IGFBP-3 exhibit weaker growth of primary prostate tumors but higher incidence of metastatic disease. 21697285 2011
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
0.400 Biomarker group LHGDN An N-terminal fragment of insulin-like growth factor binding protein-3 (IGFBP-3) induces apoptosis in human prostate cancer cells in an IGF-independent manner. 17959403 2008
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
0.400 Biomarker group LHGDN IGFBP-3 sensitizes prostate cancer cells to interferon-gamma-induced apoptosis. 17719815 2008
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
0.400 GeneticVariation group LHGDN Induction of apoptosis in human prostate cancer cells by insulin-like growth factor binding protein-3 does not require binding to retinoid X receptor-alpha. 18162523 2008
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
0.400 GeneticVariation group LHGDN Grade-specific prostate cancer associations of IGF1 (CA)19 repeats and IGFBP3-202A/C in blacks and whites. 17668637 2007
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
0.400 PosttranslationalModification group LHGDN In silico mining identifies IGFBP3 as a novel target of methylation in prostate cancer. 17453001 2007
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
0.400 Biomarker group LHGDN Contribution of the orphan nuclear receptor Nur77 to the apoptotic action of IGFBP-3. 17434920 2007
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
0.400 AlteredExpression group LHGDN Circulating insulin-like growth factor-I and binding protein-3 and risk of prostate cancer. 16775172 2006
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
0.400 Therapeutic group CTD_human Combination therapy of insulin-like growth factor binding protein-3 and retinoid X receptor ligands synergize on prostate cancer cell apoptosis in vitro and in vivo. 16000583 2005
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
0.400 Biomarker group CTD_human Combination therapy of insulin-like growth factor binding protein-3 and retinoid X receptor ligands synergize on prostate cancer cell apoptosis in vitro and in vivo. 16000583 2005
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
0.400 AlteredExpression group LHGDN Role of insulin-like growth factor binding proteins in 1alpha,25-dihydroxyvitamin D(3)-induced growth inhibition of human prostate cancer cells. 15651061 2005
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
0.400 AlteredExpression group LHGDN cDNA microarray analysis with amplified RNA after isolation of intact cellular RNA from neoplastic and non-neoplastic prostate tissue separated by laser microdissections. 15067329 2004
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
0.400 Biomarker group CTD_human Cross-species global and subset gene expression profiling identifies genes involved in prostate cancer response to selenium. 15318950 2004
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
0.400 Therapeutic group CTD_human Cross-species global and subset gene expression profiling identifies genes involved in prostate cancer response to selenium. 15318950 2004
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
0.400 Biomarker group LHGDN Insulin-like growth factor binding protein-3 induces early apoptosis in malignant prostate cancer cells and inhibits tumor formation in vivo. 11948969 2002
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
0.400 Biomarker group LHGDN Insulin-like growth factor-I (IGF-I) and IGF binding protein-3 as predictors of advanced-stage prostate cancer. 12122101 2002
Entrez Id: 3486
Gene Symbol: IGFBP3
IGFBP3
0.400 GeneticVariation group LHGDN Insulin-like growth factor (IGF)-binding protein-3 mutants that do not bind IGF-I or IGF-II stimulate apoptosis in human prostate cancer cells. 11784719 2002