Gene: NKX3-1 ×
Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1 		0.600 Biomarker group BEFREE Treatment of mouse xenograft prostate tumors with intratumoral delivery of NKX3-1 saRNA formulated in lipid nanoparticles significantly inhibited tumor growth and prolonged animal survival. 23836514 2013
Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1 		0.600 Biomarker group BEFREE The NKX3-1 gene is a homeobox gene required for prostate tumor progression, but how it functions is unclear. 22083957 2012
Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1 		0.600 Biomarker group CTD_human Exome sequencing identifies recurrent SPOP, FOXA1 and MED12 mutations in prostate cancer. 22610119 2012
Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1 		0.600 AlteredExpression group LHGDN Ubiquitination by TOPORS regulates the prostate tumor suppressor NKX3.1. 18077445 2008
Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1 		0.600 AlteredExpression group LHGDN Loss of NKX3.1 favors vascular endothelial growth factor-C expression in prostate cancer. 18974119 2008
Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1 		0.600 Biomarker group CTD_human Integrative molecular concept modeling of prostate cancer progression. 17173048 2007
Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1 		0.600 AlteredExpression group LHGDN Expression of Nkx3.1 enhances 17beta-estradiol anti-tumor action in PC3 human prostate cancer cells. 17486276 2007
Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1 		0.600 AlteredExpression group LHGDN NKX3.1 stabilizes p53, inhibits AKT activation, and blocks prostate cancer initiation caused by PTEN loss. 16697957 2006
Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1 		0.600 AlteredExpression group LHGDN p53 overexpression represses androgen-mediated induction of NKX3.1 in a prostate cancer cell line. 17202838 2006
Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1 		0.600 Biomarker group CTD_human p53 overexpression represses androgen-mediated induction of NKX3.1 in a prostate cancer cell line. 17202838 2006
Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1 		0.600 Biomarker group CTD_human Transcriptional regulation of the homeobox gene NKX3.1 by all-trans retinoic acid in prostate cancer cells. 16817226 2006
Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1 		0.600 GeneticVariation group LHGDN Germ-line mutation of NKX3.1 cosegregates with hereditary prostate cancer and alters the homeodomain structure and function. 16397218 2006
Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1 		0.600 Biomarker group LHGDN Identification of an inhibitory cis-element in the promoter region of human homeobox gene NKX3.1. 16845664 2006
Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1 		0.600 AlteredExpression group LHGDN Deletion, methylation, and expression of the NKX3.1 suppressor gene in primary human prostate cancer. 15734999 2005
Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1 		0.600 Biomarker group LHGDN Analysis of androgen regulated homeobox gene NKX3.1 during prostate carcinogenesis. 15311057 2004
Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1 		0.600 Biomarker group MGD Targeted disruption of the Nkx3.1 gene in mice results in morphogenetic defects of minor salivary glands: parallels to glandular duct morphogenesis in prostate. 10906459 2000
Entrez Id: 4824
Gene Symbol: NKX3-1
NKX3-1 		0.600 Biomarker group MGD Roles for Nkx3.1 in prostate development and cancer. 10215624 1999