×
Entrez Id:
6387
Gene Symbol:
CXCL12
CXCL12
0.400
Biomarker
group
BEFREE
These findings support the development of novel therapeutics targeting the CXCL12 /CXCR4 axis as an ancillary to those targeting the androgen/AR axis to effectively treat castration resistant/recurrent prostate tumors .
22245379
2012
×
Entrez Id:
6387
Gene Symbol:
CXCL12
CXCL12
0.400
Biomarker
group
LHGDN
CXCL12/CXCR4 transactivates HER2 in lipid rafts of prostate cancer cells and promotes growth of metastatic deposits in bone.
18337451
2008
×
Entrez Id:
6387
Gene Symbol:
CXCL12
CXCL12
0.400
Biomarker
group
LHGDN
CD26/dipeptidyl peptidase IV regulates prostate cancer metastasis by degrading SDF-1/CXCL12.
18563594
2008
×
Entrez Id:
6387
Gene Symbol:
CXCL12
CXCL12
0.400
GeneticVariation
group
LHGDN
CXCL12 G801A polymorphism is a risk factor for sporadic prostate cancer susceptibility.
17785557
2007
×
Entrez Id:
6387
Gene Symbol:
CXCL12
CXCL12
0.400
Biomarker
group
LHGDN
Expression and activation of alpha v beta 3 integrins by SDF-1/CXC12 increases the aggressiveness of prostate cancer cells.
17034033
2007
×
Entrez Id:
6387
Gene Symbol:
CXCL12
CXCL12
0.400
Biomarker
group
CTD_human
CXCL12 G801A polymorphism is a risk factor for sporadic prostate cancer susceptibility.
17785557
2007
×
Entrez Id:
6387
Gene Symbol:
CXCL12
CXCL12
0.400
AlteredExpression
group
LHGDN
CXCL12/CXCR4 signaling activates Akt-1 and MMP-9 expression in prostate cancer cells: the role of bone microenvironment-associated CXCL12.
16114056
2006
×
Entrez Id:
6387
Gene Symbol:
CXCL12
CXCL12
0.400
Biomarker
group
LHGDN
The importance of the CXCL12-CXCR4 chemokine ligand-receptor interaction in prostate cancer metastasis.
15844659
2004
×
Entrez Id:
6387
Gene Symbol:
CXCL12
CXCL12
0.400
Biomarker
group
LHGDN
CXCL12-CXCR4 interactions modulate prostate cancer cell migration, metalloproteinase expression and invasion.
15467730
2004
×
Entrez Id:
6387
Gene Symbol:
CXCL12
CXCL12
0.400
Biomarker
group
LHGDN
CXCR4 and CXCL12 (SDF-1) in prostate cancer: inhibitory effects of human single chain Fv antibodies.
15328206
2004
×
Entrez Id:
6387
Gene Symbol:
CXCL12
CXCL12
0.400
AlteredExpression
group
LHGDN
Expression of CXCR4 and CXCL12 (SDF-1) in human prostate cancers (PCa) in vivo.
12761880
2003
×
Entrez Id:
6387
Gene Symbol:
CXCL12
CXCL12
0.400
AlteredExpression
group
LHGDN
Use of the stromal cell-derived factor-1/CXCR4 pathway in prostate cancer metastasis to bone.
11912162
2002